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Primaquine homodimers as potential antiplasmodial and anticancer agents.
Pavić K, Rubinić B, Rajić Z, Fontinha D, Prudêncio M, Uzelac L, Kralj M, Held J, Zorc B. Pavić K, et al. Among authors: prudencio m. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126614. doi: 10.1016/j.bmcl.2019.08.018. Epub 2019 Aug 10. Bioorg Med Chem Lett. 2019. PMID: 31431364
Imidazoquines as antimalarial and antipneumocystis agents.
Vale N, Prudêncio M, Marques CA, Collins MS, Gut J, Nogueira F, Matos J, Rosenthal PJ, Cushion MT, do Rosário VE, Mota MM, Moreira R, Gomes P. Vale N, et al. Among authors: prudencio m. J Med Chem. 2009 Dec 10;52(23):7800-7. doi: 10.1021/jm900738c. J Med Chem. 2009. PMID: 19799426 Free PMC article.
N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads.
Pérez BC, Teixeira C, Albuquerque IS, Gut J, Rosenthal PJ, Gomes JR, Prudêncio M, Gomes P. Pérez BC, et al. Among authors: prudencio m. J Med Chem. 2013 Jan 24;56(2):556-67. doi: 10.1021/jm301654b. Epub 2013 Jan 8. J Med Chem. 2013. PMID: 23273038 Free article.
Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.
Rodrigues T, da Cruz FP, Lafuente-Monasterio MJ, Gonçalves D, Ressurreição AS, Sitoe AR, Bronze MR, Gut J, Schneider G, Mota MM, Rosenthal PJ, Prudêncio M, Gamo FJ, Lopes F, Moreira R. Rodrigues T, et al. Among authors: prudencio m. J Med Chem. 2013 Jun 13;56(11):4811-5. doi: 10.1021/jm400246e. Epub 2013 May 23. J Med Chem. 2013. PMID: 23701465
Structural optimization of quinolon-4(1H)-imines as dual-stage antimalarials: toward increased potency and metabolic stability.
Ressurreição AS, Gonçalves D, Sitoe AR, Albuquerque IS, Gut J, Góis A, Gonçalves LM, Bronze MR, Hanscheid T, Biagini GA, Rosenthal PJ, Prudêncio M, O'Neill P, Mota MM, Lopes F, Moreira R. Ressurreição AS, et al. Among authors: prudencio m. J Med Chem. 2013 Oct 10;56(19):7679-90. doi: 10.1021/jm4011466. Epub 2013 Sep 30. J Med Chem. 2013. PMID: 24020770
Flavones as isosteres of 4(1H)-quinolones: discovery of ligand efficient and dual stage antimalarial lead compounds.
Rodrigues T, Ressurreição AS, da Cruz FP, Albuquerque IS, Gut J, Carrasco MP, Gonçalves D, Guedes RC, dos Santos DJ, Mota MM, Rosenthal PJ, Moreira R, Prudêncio M, Lopes F. Rodrigues T, et al. Among authors: prudencio m. Eur J Med Chem. 2013 Nov;69:872-80. doi: 10.1016/j.ejmech.2013.09.008. Epub 2013 Sep 20. Eur J Med Chem. 2013. PMID: 24125849
241 results