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Primaquine hybrids as promising antimycobacterial and antimalarial agents.
Pavić K, Perković I, Pospíšilová Š, Machado M, Fontinha D, Prudêncio M, Jampilek J, Coffey A, Endersen L, Rimac H, Zorc B. Pavić K, et al. Among authors: prudencio m. Eur J Med Chem. 2018 Jan 1;143:769-779. doi: 10.1016/j.ejmech.2017.11.083. Epub 2017 Dec 2. Eur J Med Chem. 2018. PMID: 29220797
Imidazoquines as antimalarial and antipneumocystis agents.
Vale N, Prudêncio M, Marques CA, Collins MS, Gut J, Nogueira F, Matos J, Rosenthal PJ, Cushion MT, do Rosário VE, Mota MM, Moreira R, Gomes P. Vale N, et al. Among authors: prudencio m. J Med Chem. 2009 Dec 10;52(23):7800-7. doi: 10.1021/jm900738c. J Med Chem. 2009. PMID: 19799426 Free PMC article.
Targeting the liver stage of malaria parasites: a yet unmet goal.
Rodrigues T, Prudêncio M, Moreira R, Mota MM, Lopes F. Rodrigues T, et al. Among authors: prudencio m. J Med Chem. 2012 Feb 9;55(3):995-1012. doi: 10.1021/jm201095h. Epub 2011 Dec 21. J Med Chem. 2012. PMID: 22122518 Review. No abstract available.
N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads.
Pérez BC, Teixeira C, Albuquerque IS, Gut J, Rosenthal PJ, Gomes JR, Prudêncio M, Gomes P. Pérez BC, et al. Among authors: prudencio m. J Med Chem. 2013 Jan 24;56(2):556-67. doi: 10.1021/jm301654b. Epub 2013 Jan 8. J Med Chem. 2013. PMID: 23273038 Free article.
Quinolin-4(1H)-imines are potent antiplasmodial drugs targeting the liver stage of malaria.
Rodrigues T, da Cruz FP, Lafuente-Monasterio MJ, Gonçalves D, Ressurreição AS, Sitoe AR, Bronze MR, Gut J, Schneider G, Mota MM, Rosenthal PJ, Prudêncio M, Gamo FJ, Lopes F, Moreira R. Rodrigues T, et al. Among authors: prudencio m. J Med Chem. 2013 Jun 13;56(11):4811-5. doi: 10.1021/jm400246e. Epub 2013 May 23. J Med Chem. 2013. PMID: 23701465
Structural optimization of quinolon-4(1H)-imines as dual-stage antimalarials: toward increased potency and metabolic stability.
Ressurreição AS, Gonçalves D, Sitoe AR, Albuquerque IS, Gut J, Góis A, Gonçalves LM, Bronze MR, Hanscheid T, Biagini GA, Rosenthal PJ, Prudêncio M, O'Neill P, Mota MM, Lopes F, Moreira R. Ressurreição AS, et al. Among authors: prudencio m. J Med Chem. 2013 Oct 10;56(19):7679-90. doi: 10.1021/jm4011466. Epub 2013 Sep 30. J Med Chem. 2013. PMID: 24020770
241 results