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C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps.
Silva BM, Gomes GF, Veras FP, Cambier S, Silva GV, Quadros AU, Caetité DB, Nascimento DC, Silva CM, Silva JC, Damasceno S, Schneider AH, Beretta F, Batah SS, Castro IM, Paiva IM, Rodrigues T, Salina A, Martins R, Cebinelli GC, Bibo NL, Jorge DM, Nakaya HI, Zamboni DS, Leiria LO, Fabro AT, Alves-Filho JC, Arruda E, Louzada-Junior P, Oliveira RD, Cunha LD, Van Mol P, Vanderbeke L, Feys S, Wauters E, Brandolini L, Aramini A, Cunha FQ, Köhl J, Allegretti M, Lambrechts D, Wauters J, Proost P, Cunha TM. Silva BM, et al. Among authors: proost p. J Clin Invest. 2023 Jun 15;133(12):e163105. doi: 10.1172/JCI163105. J Clin Invest. 2023. PMID: 37104043 Free PMC article.
Establishing a Unified COVID-19 "Immunome": Integrating Coronavirus Pathogenesis and Host Immunopathology.
Wauters E, Thevissen K, Wouters C, Bosisio FM, De Smet F, Gunst J, Humblet-Baron S, Lambrechts D, Liston A, Matthys P, Neyts J, Proost P, Weynand B, Wauters J, Tejpar S, Garg AD. Wauters E, et al. Among authors: proost p. Front Immunol. 2020 Jul 3;11:1642. doi: 10.3389/fimmu.2020.01642. eCollection 2020. Front Immunol. 2020. PMID: 32719686 Free PMC article. No abstract available.
Increased IL-10-producing regulatory T cells are characteristic of severe cases of COVID-19.
Neumann J, Prezzemolo T, Vanderbeke L, Roca CP, Gerbaux M, Janssens S, Willemsen M, Burton O, Van Mol P, Van Herck Y; CONTAGIOUS co‐authors; Wauters J, Wauters E, Liston A, Humblet-Baron S. Neumann J, et al. Clin Transl Immunology. 2020 Nov 13;9(11):e1204. doi: 10.1002/cti2.1204. eCollection 2020. Clin Transl Immunology. 2020. PMID: 33209300 Free PMC article.
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages.
Wauters E, Van Mol P, Garg AD, Jansen S, Van Herck Y, Vanderbeke L, Bassez A, Boeckx B, Malengier-Devlies B, Timmerman A, Van Brussel T, Van Buyten T, Schepers R, Heylen E, Dauwe D, Dooms C, Gunst J, Hermans G, Meersseman P, Testelmans D, Yserbyt J, Tejpar S, De Wever W, Matthys P; CONTAGIOUS collaborators; Neyts J, Wauters J, Qian J, Lambrechts D. Wauters E, et al. Cell Res. 2021 Mar;31(3):272-290. doi: 10.1038/s41422-020-00455-9. Epub 2021 Jan 21. Cell Res. 2021. PMID: 33473155 Free PMC article.
High dimensional profiling identifies specific immune types along the recovery trajectories of critically ill COVID19 patients.
Penttilä PA, Van Gassen S, Panovska D, Vanderbeke L, Van Herck Y, Quintelier K, Emmaneel A, Filtjens J, Malengier-Devlies B, Ahmadzadeh K, Van Mol P, Borràs DM, Antoranz A, Bosisio FM, Wauters E, Martinod K, Matthys P, Saeys Y, Garg AD, Wauters J, De Smet F; CONTAGIOUS consortium. Penttilä PA, et al. Cell Mol Life Sci. 2021 Apr;78(8):3987-4002. doi: 10.1007/s00018-021-03808-8. Epub 2021 Mar 13. Cell Mol Life Sci. 2021. PMID: 33715015 Free PMC article.
Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019.
Metzemaekers M, Cambier S, Blanter M, Vandooren J, de Carvalho AC, Malengier-Devlies B, Vanderbeke L, Jacobs C, Coenen S, Martens E, Pörtner N, Vanbrabant L, Van Mol P, Van Herck Y, Van Aerde N, Hermans G, Gunst J, Borin A, Toledo N Pereira B, Dos Sp Gomes AB, Primon Muraro S, Fabiano de Souza G, S Farias A, Proenca-Modena JL, R Vinolo MA; CONTAGIOUS Consortium; Marques PE, Wouters C, Wauters E, Struyf S, Matthys P, Opdenakker G, Marques RE, Wauters J, Gouwy M, Proost P. Metzemaekers M, et al. Among authors: proost p. Clin Transl Immunology. 2021 Apr 29;10(4):e1271. doi: 10.1002/cti2.1271. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33968405 Free PMC article.
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity.
Vanderbeke L, Van Mol P, Van Herck Y, De Smet F, Humblet-Baron S, Martinod K, Antoranz A, Arijs I, Boeckx B, Bosisio FM, Casaer M, Dauwe D, De Wever W, Dooms C, Dreesen E, Emmaneel A, Filtjens J, Gouwy M, Gunst J, Hermans G, Jansen S, Lagrou K, Liston A, Lorent N, Meersseman P, Mercier T, Neyts J, Odent J, Panovska D, Penttila PA, Pollet E, Proost P, Qian J, Quintelier K, Raes J, Rex S, Saeys Y, Sprooten J, Tejpar S, Testelmans D, Thevissen K, Van Buyten T, Vandenhaute J, Van Gassen S, Velásquez Pereira LC, Vos R, Weynand B, Wilmer A, Yserbyt J, Garg AD, Matthys P, Wouters C, Lambrechts D, Wauters E, Wauters J. Vanderbeke L, et al. Among authors: proost p. Nat Commun. 2021 Jul 5;12(1):4117. doi: 10.1038/s41467-021-24360-w. Nat Commun. 2021. PMID: 34226537 Free PMC article.
363 results