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Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein.
Yerabham ASK, Müller-Schiffmann A, Ziehm T, Stadler A, Köber S, Indurkhya X, Marreiros R, Trossbach SV, Bradshaw NJ, Prikulis I, Willbold D, Weiergräber OH, Korth C. Yerabham ASK, et al. Among authors: prikulis i. PLoS One. 2018 Jan 11;13(1):e0191162. doi: 10.1371/journal.pone.0191162. eCollection 2018. PLoS One. 2018. PMID: 29324815 Free PMC article.
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.
Bader V, Tomppo L, Trossbach SV, Bradshaw NJ, Prikulis I, Leliveld SR, Lin CY, Ishizuka K, Sawa A, Ramos A, Rosa I, García Á, Requena JR, Hipolito M, Rai N, Nwulia E, Henning U, Ferrea S, Luckhaus C, Ekelund J, Veijola J, Järvelin MR, Hennah W, Korth C. Bader V, et al. Among authors: prikulis i. Hum Mol Genet. 2012 Oct 15;21(20):4406-18. doi: 10.1093/hmg/dds273. Epub 2012 Jul 13. Hum Mol Genet. 2012. PMID: 22798627 Free PMC article.
Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation.
Marreiros R, Müller-Schiffmann A, Trossbach SV, Prikulis I, Hänsch S, Weidtkamp-Peters S, Moreira AR, Sahu S, Soloviev I, Selvarajah S, Lingappa VR, Korth C. Marreiros R, et al. Among authors: prikulis i. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6741-6751. doi: 10.1073/pnas.1906466117. Epub 2020 Mar 9. Proc Natl Acad Sci U S A. 2020. PMID: 32152117 Free PMC article.
Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade.
Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Seshadri S, et al. Among authors: prikulis i. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5622-7. doi: 10.1073/pnas.0909284107. Epub 2010 Mar 8. Proc Natl Acad Sci U S A. 2010. PMID: 20212127 Free PMC article.
Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.
Trossbach SV, Bader V, Hecher L, Pum ME, Masoud ST, Prikulis I, Schäble S, de Souza Silva MA, Su P, Boulat B, Chwiesko C, Poschmann G, Stühler K, Lohr KM, Stout KA, Oskamp A, Godsave SF, Müller-Schiffmann A, Bilzer T, Steiner H, Peters PJ, Bauer A, Sauvage M, Ramsey AJ, Miller GW, Liu F, Seeman P, Brandon NJ, Huston JP, Korth C. Trossbach SV, et al. Among authors: prikulis i. Mol Psychiatry. 2016 Nov;21(11):1561-1572. doi: 10.1038/mp.2015.194. Epub 2016 Jan 12. Mol Psychiatry. 2016. PMID: 26754951 Free PMC article.
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