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Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity.
Clippinger AJ, Allen D, Behrsing H, BéruBé KA, Bolger MB, Casey W, DeLorme M, Gaça M, Gehen SC, Glover K, Hayden P, Hinderliter P, Hotchkiss JA, Iskandar A, Keyser B, Luettich K, Ma-Hock L, Maione AG, Makena P, Melbourne J, Milchak L, Ng SP, Paini A, Page K, Patlewicz G, Prieto P, Raabe H, Reinke EN, Roper C, Rose J, Sharma M, Spoo W, Thorne PS, Wilson DM, Jarabek AM. Clippinger AJ, et al. Among authors: prieto p. Toxicol In Vitro. 2018 Oct;52:131-145. doi: 10.1016/j.tiv.2018.06.009. Epub 2018 Jun 20. Toxicol In Vitro. 2018. PMID: 29908304 Free PMC article. Review.
Assessment of the predictive capacity of the 3T3 Neutral Red Uptake cytotoxicity test method to identify substances not classified for acute oral toxicity (LD50>2000 mg/kg): results of an ECVAM validation study.
Prieto P, Cole T, Curren R, Gibson RM, Liebsch M, Raabe H, Tuomainen AM, Whelan M, Kinsner-Ovaskainen A. Prieto P, et al. Regul Toxicol Pharmacol. 2013 Apr;65(3):344-65. doi: 10.1016/j.yrtph.2012.11.013. Epub 2012 Dec 13. Regul Toxicol Pharmacol. 2013. PMID: 23246604
The virtual cell based assay: Current status and future perspectives.
Graepel R, Lamon L, Asturiol D, Berggren E, Joossens E, Paini A, Prieto P, Whelan M, Worth A. Graepel R, et al. Among authors: prieto p. Toxicol In Vitro. 2017 Dec;45(Pt 2):258-267. doi: 10.1016/j.tiv.2017.01.009. Epub 2017 Jan 18. Toxicol In Vitro. 2017. PMID: 28108195 Free PMC article.
ECVAM's ongoing activities in the area of acute oral toxicity.
Kinsner-Ovaskainen A, Bulgheroni A, Hartung T, Prieto P. Kinsner-Ovaskainen A, et al. Among authors: prieto p. Toxicol In Vitro. 2009 Dec;23(8):1535-40. doi: 10.1016/j.tiv.2009.07.004. Epub 2009 Jul 8. Toxicol In Vitro. 2009. PMID: 19591916
Acutoxbase, an innovative database for in vitro acute toxicity studies.
Kinsner-Ovaskainen A, Rzepka R, Rudowski R, Coecke S, Cole T, Prieto P. Kinsner-Ovaskainen A, et al. Among authors: prieto p. Toxicol In Vitro. 2009 Apr;23(3):476-85. doi: 10.1016/j.tiv.2008.12.019. Epub 2008 Dec 30. Toxicol In Vitro. 2009. PMID: 19159672
Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies.
Pistollato F, Madia F, Corvi R, Munn S, Grignard E, Paini A, Worth A, Bal-Price A, Prieto P, Casati S, Berggren E, Bopp SK, Zuang V. Pistollato F, et al. Among authors: prieto p. Arch Toxicol. 2021 Jun;95(6):1867-1897. doi: 10.1007/s00204-021-03034-y. Epub 2021 Apr 13. Arch Toxicol. 2021. PMID: 33851225 Free PMC article. Review.
The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: results from the European Project ACuteTox.
Prieto P, Kinsner-Ovaskainen A, Stanzel S, Albella B, Artursson P, Campillo N, Cecchelli R, Cerrato L, Díaz L, Di Consiglio E, Guerra A, Gombau L, Herrera G, Honegger P, Landry C, O'Connor JE, Páez JA, Quintas G, Svensson R, Turco L, Zurich MG, Zurbano MJ, Kopp-Schneider A. Prieto P, et al. Toxicol In Vitro. 2013 Jun;27(4):1357-76. doi: 10.1016/j.tiv.2012.07.013. Epub 2012 Aug 16. Toxicol In Vitro. 2013. PMID: 22922246
469 results