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A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR.
Biochim Biophys Acta Proteins Proteom. 2019 Mar;1867(3):248-258. doi: 10.1016/j.bbapap.2018.12.003. Epub 2018 Dec 13.
Biochim Biophys Acta Proteins Proteom. 2019.
PMID: 30553830
Free article.
A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.
Prevet H, Moune M, Tanina A, Kemmer C, Herledan A, Frita R, Wohlkönig A, Bourotte M, Villemagne B, Leroux F, Gitzinger M, Baulard AR, Déprez B, Wintjens R, Willand N, Flipo M.
Prevet H, et al.
Eur J Med Chem. 2019 Apr 1;167:426-438. doi: 10.1016/j.ejmech.2019.02.023. Epub 2019 Feb 10.
Eur J Med Chem. 2019.
PMID: 30784877
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Labelled chemical probes for demonstrating direct target engagement in living systems.
Prevet H, Collins I.
Prevet H, et al.
Future Med Chem. 2019 May;11(10):1195-1224. doi: 10.4155/fmc-2018-0370.
Future Med Chem. 2019.
PMID: 31280668
Free article.
Review.
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Discovery of 2-(3-Benzamidopropanamido)thiazole-5-carboxylate Inhibitors of the Kinesin HSET (KIFC1) and the Development of Cellular Target Engagement Probes.
Saint-Dizier F, Matthews TP, Gregson AM, Prevet H, McHardy T, Colombano G, Saville H, Rowlands M, Ewens C, McAndrew PC, Tomlin K, Guillotin D, Mak GW, Drosopoulos K, Poursaitidis I, Burke R, van Montfort R, Linardopoulos S, Collins I.
Saint-Dizier F, et al. Among authors: prevet h.
J Med Chem. 2023 Feb 23;66(4):2622-2645. doi: 10.1021/acs.jmedchem.2c01591. Epub 2023 Feb 7.
J Med Chem. 2023.
PMID: 36749938
Free PMC article.
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Isothiourea-catalyzed asymmetric synthesis of β-lactams and β-amino esters from arylacetic acid derivatives and N-sulfonylaldimines.
Smith SR, Douglas J, Prevet H, Shapland P, Slawin AM, Smith AD.
Smith SR, et al. Among authors: prevet h.
J Org Chem. 2014 Feb 21;79(4):1626-39. doi: 10.1021/jo402590m. Epub 2014 Feb 5.
J Org Chem. 2014.
PMID: 24432704
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