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At-home wearables and machine learning sensitively capture disease progression in amyotrophic lateral sclerosis.
Nat Commun. 2023 Aug 21;14(1):5080. doi: 10.1038/s41467-023-40917-3.
Nat Commun. 2023.
PMID: 37604821
Free PMC article.
A machine-learning based objective measure for ALS disease severity.
Vieira FG, Venugopalan S, Premasiri AS, McNally M, Jansen A, McCloskey K, Brenner MP, Perrin S.
Vieira FG, et al. Among authors: premasiri as.
NPJ Digit Med. 2022 Apr 8;5(1):45. doi: 10.1038/s41746-022-00588-8.
NPJ Digit Med. 2022.
PMID: 35396385
Free PMC article.
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Primary Neurons and Differentiated NSC-34 Cells Are More Susceptible to Arginine-Rich ALS Dipeptide Repeat Protein-Associated Toxicity than Non-Differentiated NSC-34 and CHO Cells.
Gill AL, Wang MZ, Levine B, Premasiri A, Vieira FG.
Gill AL, et al. Among authors: premasiri a.
Int J Mol Sci. 2019 Dec 11;20(24):6238. doi: 10.3390/ijms20246238.
Int J Mol Sci. 2019.
PMID: 31835664
Free PMC article.
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Type I PRMT Inhibition Protects Against C9ORF72 Arginine-Rich Dipeptide Repeat Toxicity.
Premasiri AS, Gill AL, Vieira FG.
Premasiri AS, et al.
Front Pharmacol. 2020 Sep 8;11:569661. doi: 10.3389/fphar.2020.569661. eCollection 2020.
Front Pharmacol. 2020.
PMID: 33013410
Free PMC article.
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Hypothesis and Theory: Roles of Arginine Methylation in C9orf72-Mediated ALS and FTD.
Gill AL, Premasiri AS, Vieira FG.
Gill AL, et al. Among authors: premasiri as.
Front Cell Neurosci. 2021 Mar 23;15:633668. doi: 10.3389/fncel.2021.633668. eCollection 2021.
Front Cell Neurosci. 2021.
PMID: 33833668
Free PMC article.
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Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF3-Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation.
Sieber JD, Rodriguez S, Frutos R, Buono F, Zhang Y, Li N, Qu B, Premasiri A, Li Z, Han ZS, Xu Y, Byrne D, Haddad N, Lorenz J, Grinberg N, Kurouski D, Lee H, Narayanan B, Nummy L, Mulder J, Brown JD, Granger A, Gao J, Krawiec M, Williams Z, Pennino S, Song JJ, Hossain A, Yee NK, Busacca C, Roschangar F, Xin Y, Mao Z, Zhang X, Hong Y, Senanayake CH.
Sieber JD, et al. Among authors: premasiri a.
J Org Chem. 2018 Feb 2;83(3):1448-1461. doi: 10.1021/acs.joc.7b03022. Epub 2018 Jan 23.
J Org Chem. 2018.
PMID: 29323903
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Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.
Reeves JT, Fandrick DR, Tan Z, Song JJ, Rodriguez S, Qu B, Kim S, Niemeier O, Li Z, Byrne D, Campbell S, Chitroda A, DeCroos P, Fachinger T, Fuchs V, Gonnella NC, Grinberg N, Haddad N, Jäger B, Lee H, Lorenz JC, Ma S, Narayanan BA, Nummy LJ, Premasiri A, Roschangar F, Sarvestani M, Shen S, Spinelli E, Sun X, Varsolona RJ, Yee N, Brenner M, Senanayake CH.
Reeves JT, et al. Among authors: premasiri a.
J Org Chem. 2013 Apr 19;78(8):3616-35. doi: 10.1021/jo400079z. Epub 2013 Apr 1.
J Org Chem. 2013.
PMID: 23544738
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Asymmetric methallylation of ketones catalyzed by a highly active organocatalyst 3,3'-F2-BINOL.
Zhang Y, Li N, Qu B, Ma S, Lee H, Gonnella NC, Gao J, Li W, Tan Z, Reeves JT, Wang J, Lorenz JC, Li G, Reeves DC, Premasiri A, Grinberg N, Haddad N, Lu BZ, Song JJ, Senanayake CH.
Zhang Y, et al. Among authors: premasiri a.
Org Lett. 2013 Apr 5;15(7):1710-3. doi: 10.1021/ol400498a. Epub 2013 Mar 25.
Org Lett. 2013.
PMID: 23527954
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