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CDK4/6-MEK Inhibition in MPNSTs Causes Plasma Cell Infiltration, Sensitization to PD-L1 Blockade, and Tumor Regression.
Kohlmeyer JL, Lingo JJ, Kaemmer CA, Scherer A, Warrier A, Voigt E, Raygoza Garay JA, McGivney GR, Brockman QR, Tang A, Calizo A, Pollard K, Zhang X, Hirbe AC, Pratilas CA, Leidinger M, Breheny P, Chimenti MS, Sieren JC, Monga V, Tanas MR, Meyerholz DK, Darbro BW, Dodd RD, Quelle DE. Kohlmeyer JL, et al. Among authors: pratilas ca. Clin Cancer Res. 2023 Sep 1;29(17):3484-3497. doi: 10.1158/1078-0432.CCR-23-0749. Clin Cancer Res. 2023. PMID: 37410426 Free PMC article.
Ifosfamide dose-intensification for patients with metastatic Ewing sarcoma.
Magnan H, Goodbody CM, Riedel E, Pratilas CA, Wexler LH, Chou AJ. Magnan H, et al. Among authors: pratilas ca. Pediatr Blood Cancer. 2015 Apr;62(4):594-7. doi: 10.1002/pbc.25373. Epub 2015 Jan 28. Pediatr Blood Cancer. 2015. PMID: 25630954 Free PMC article. Clinical Trial.
Targeting oncogenic BRAF in human cancer.
Pratilas CA, Xing F, Solit DB. Pratilas CA, et al. Curr Top Microbiol Immunol. 2012;355:83-98. doi: 10.1007/82_2011_162. Curr Top Microbiol Immunol. 2012. PMID: 21818706 Free PMC article.
The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.
Okada T, Sinha S, Esposito I, Schiavon G, López-Lago MA, Su W, Pratilas CA, Abele C, Hernandez JM, Ohara M, Okada M, Viale A, Heguy A, Socci ND, Sapino A, Seshan VE, Long S, Inghirami G, Rosen N, Giancotti FG. Okada T, et al. Among authors: pratilas ca. Nat Cell Biol. 2015 Jan;17(1):81-94. doi: 10.1038/ncb3082. Epub 2014 Dec 22. Nat Cell Biol. 2015. PMID: 25531777 Free PMC article.
The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner.
Joseph EW, Pratilas CA, Poulikakos PI, Tadi M, Wang W, Taylor BS, Halilovic E, Persaud Y, Xing F, Viale A, Tsai J, Chapman PB, Bollag G, Solit DB, Rosen N. Joseph EW, et al. Among authors: pratilas ca. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14903-8. doi: 10.1073/pnas.1008990107. Epub 2010 Jul 28. Proc Natl Acad Sci U S A. 2010. PMID: 20668238 Free PMC article.
A clinically and genomically annotated nerve sheath tumor biospecimen repository.
Pollard K, Banerjee J, Doan X, Wang J, Guo X, Allaway R, Langmead S, Slobogean B, Meyer CF, Loeb DM, Morris CD, Belzberg AJ, Blakeley JO, Rodriguez FJ, Guinney J, Gosline SJC, Pratilas CA. Pollard K, et al. Among authors: pratilas ca. Sci Data. 2020 Jun 19;7(1):184. doi: 10.1038/s41597-020-0508-5. Sci Data. 2020. PMID: 32561749 Free PMC article.
88 results