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BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.
Yoneshiro T, Wang Q, Tajima K, Matsushita M, Maki H, Igarashi K, Dai Z, White PJ, McGarrah RW, Ilkayeva OR, Deleye Y, Oguri Y, Kuroda M, Ikeda K, Li H, Ueno A, Ohishi M, Ishikawa T, Kim K, Chen Y, Sponton CH, Pradhan RN, Majd H, Greiner VJ, Yoneshiro M, Brown Z, Chondronikola M, Takahashi H, Goto T, Kawada T, Sidossis L, Szoka FC, McManus MT, Saito M, Soga T, Kajimura S. Yoneshiro T, et al. Among authors: pradhan rn. Nature. 2019 Aug;572(7771):614-619. doi: 10.1038/s41586-019-1503-x. Epub 2019 Aug 21. Nature. 2019. PMID: 31435015 Free PMC article.
The regulation of glucose and lipid homeostasis via PLTP as a mediator of BAT-liver communication.
Sponton CH, Hosono T, Taura J, Jedrychowski MP, Yoneshiro T, Wang Q, Takahashi M, Matsui Y, Ikeda K, Oguri Y, Tajima K, Shinoda K, Pradhan RN, Chen Y, Brown Z, Roberts LS, Ward CC, Taoka H, Yokoyama Y, Watanabe M, Karasawa H, Nomura DK, Kajimura S. Sponton CH, et al. Among authors: pradhan rn. EMBO Rep. 2020 Sep 3;21(9):e49828. doi: 10.15252/embr.201949828. Epub 2020 Jul 16. EMBO Rep. 2020. PMID: 32672883 Free PMC article.
Post-translational control of beige fat biogenesis by PRDM16 stabilization.
Wang Q, Li H, Tajima K, Verkerke ARP, Taxin ZH, Hou Z, Cole JB, Li F, Wong J, Abe I, Pradhan RN, Yamamuro T, Yoneshiro T, Hirschhorn JN, Kajimura S. Wang Q, et al. Among authors: pradhan rn. Nature. 2022 Sep;609(7925):151-158. doi: 10.1038/s41586-022-05067-4. Epub 2022 Aug 17. Nature. 2022. PMID: 35978186 Free PMC article.
CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling.
Oguri Y, Shinoda K, Kim H, Alba DL, Bolus WR, Wang Q, Brown Z, Pradhan RN, Tajima K, Yoneshiro T, Ikeda K, Chen Y, Cheang RT, Tsujino K, Kim CR, Greiner VJ, Datta R, Yang CD, Atabai K, McManus MT, Koliwad SK, Spiegelman BM, Kajimura S. Oguri Y, et al. Among authors: pradhan rn. Cell. 2020 Aug 6;182(3):563-577.e20. doi: 10.1016/j.cell.2020.06.021. Epub 2020 Jul 1. Cell. 2020. PMID: 32615086 Free PMC article.
Cross-tissue organization of the fibroblast lineage.
Buechler MB, Pradhan RN, Krishnamurty AT, Cox C, Calviello AK, Wang AW, Yang YA, Tam L, Caothien R, Roose-Girma M, Modrusan Z, Arron JR, Bourgon R, Müller S, Turley SJ. Buechler MB, et al. Among authors: pradhan rn. Nature. 2021 May;593(7860):575-579. doi: 10.1038/s41586-021-03549-5. Epub 2021 May 12. Nature. 2021. PMID: 33981032
LRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity.
Krishnamurty AT, Shyer JA, Thai M, Gandham V, Buechler MB, Yang YA, Pradhan RN, Wang AW, Sanchez PL, Qu Y, Breart B, Chalouni C, Dunlap D, Ziai J, Elstrott J, Zacharias N, Mao W, Rowntree RK, Sadowsky J, Lewis GD, Pillow TH, Nabet BY, Banchereau R, Tam L, Caothien R, Bacarro N, Roose-Girma M, Modrusan Z, Mariathasan S, Müller S, Turley SJ. Krishnamurty AT, et al. Among authors: pradhan rn. Nature. 2022 Nov;611(7934):148-154. doi: 10.1038/s41586-022-05272-1. Epub 2022 Sep 28. Nature. 2022. PMID: 36171287 Free PMC article.
A microRNA expression and regulatory element activity atlas of the mouse immune system.
Rose SA, Wroblewska A, Dhainaut M, Yoshida H, Shaffer JM, Bektesevic A, Ben-Zvi B, Rhoads A, Kim EY, Yu B, Lavin Y, Merad M, Buenrostro JD, Brown BD; Immunological Genome Consortium. Rose SA, et al. Nat Immunol. 2021 Jul;22(7):914-927. doi: 10.1038/s41590-021-00944-y. Epub 2021 Jun 7. Nat Immunol. 2021. PMID: 34099919 Free PMC article.
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes.
Kiner E, Willie E, Vijaykumar B, Chowdhary K, Schmutz H, Chandler J, Schnell A, Thakore PI, LeGros G, Mostafavi S, Mathis D, Benoist C; Immunological Genome Project Consortium. Kiner E, et al. Nat Immunol. 2021 Feb;22(2):216-228. doi: 10.1038/s41590-020-00836-7. Epub 2021 Jan 18. Nat Immunol. 2021. PMID: 33462454 Free PMC article.
25 results