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Short-term exposure to air pollution (PM2.5) induces hypothalamic inflammation, and long-term leads to leptin resistance and obesity via Tlr4/Ikbke in mice.
Campolim CM, Weissmann L, Ferreira CKO, Zordão OP, Dornellas APS, de Castro G, Zanotto TM, Boico VF, Quaresma PGF, Lima RPA, Donato J Jr, Veras MM, Saldiva PHN, Kim YB, Prada PO. Campolim CM, et al. Among authors: prada po. Sci Rep. 2020 Jun 23;10(1):10160. doi: 10.1038/s41598-020-67040-3. Sci Rep. 2020. PMID: 32576879 Free PMC article.
IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition.
Ropelle ER, Flores MB, Cintra DE, Rocha GZ, Pauli JR, Morari J, de Souza CT, Moraes JC, Prada PO, Guadagnini D, Marin RM, Oliveira AG, Augusto TM, Carvalho HF, Velloso LA, Saad MJ, Carvalheira JB. Ropelle ER, et al. Among authors: prada po. PLoS Biol. 2010 Aug 24;8(8):e1000465. doi: 10.1371/journal.pbio.1000465. PLoS Biol. 2010. PMID: 20808781 Free PMC article. Retracted.
Acute exercise suppresses hypothalamic PTP1B protein level and improves insulin and leptin signaling in obese rats.
Chiarreotto-Ropelle EC, Pauli LS, Katashima CK, Pimentel GD, Picardi PK, Silva VR, de Souza CT, Prada PO, Cintra DE, Carvalheira JB, Ropelle ER, Pauli JR. Chiarreotto-Ropelle EC, et al. Among authors: prada po. Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E649-59. doi: 10.1152/ajpendo.00272.2013. Epub 2013 Jul 23. Am J Physiol Endocrinol Metab. 2013. PMID: 23880311 Free article. Retracted.
67 results