Prabu-Jeyabalan M - Search Results

1

Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor.

Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Surleraux DL, et al. J Med Chem. 2005 Mar 24;48(6):1813-22. doi: 10.1021/jm049560p. J Med Chem. 2005. PMID: 15771427

2

Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor.

King NM, Prabu-Jeyabalan M, Nalivaika EA, Wigerinck P, de Béthune MP, Schiffer CA. King NM, et al. J Virol. 2004 Nov;78(21):12012-21. doi: 10.1128/JVI.78.21.12012-12021.2004. J Virol. 2004. PMID: 15479840 Free PMC article.

3

Design of HIV-1 protease inhibitors active on multidrug-resistant virus.

Surleraux DL, de Kock HA, Verschueren WG, Pille GM, Maes LJ, Peeters A, Vendeville S, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Surleraux DL, et al. Among authors: prabu jeyabalan m. J Med Chem. 2005 Mar 24;48(6):1965-73. doi: 10.1021/jm049454n. J Med Chem. 2005. PMID: 15771440

4

Combating susceptibility to drug resistance: lessons from HIV-1 protease.

King NM, Prabu-Jeyabalan M, Nalivaika EA, Schiffer CA. King NM, et al. Chem Biol. 2004 Oct;11(10):1333-8. doi: 10.1016/j.chembiol.2004.08.010. Chem Biol. 2004. PMID: 15489160

5

Lack of synergy for inhibitors targeting a multi-drug-resistant HIV-1 protease.

King NM, Melnick L, Prabu-Jeyabalan M, Nalivaika EA, Yang SS, Gao Y, Nie X, Zepp C, Heefner DL, Schiffer CA. King NM, et al. Protein Sci. 2002 Feb;11(2):418-29. doi: 10.1110/ps.25502. Protein Sci. 2002. PMID: 11790852 Free PMC article.

6

Viability of a drug-resistant human immunodeficiency virus type 1 protease variant: structural insights for better antiviral therapy.

Prabu-Jeyabalan M, Nalivaika EA, King NM, Schiffer CA. Prabu-Jeyabalan M, et al. J Virol. 2003 Jan;77(2):1306-15. doi: 10.1128/jvi.77.2.1306-1315.2003. J Virol. 2003. PMID: 12502847 Free PMC article.

7

Structural basis for coevolution of a human immunodeficiency virus type 1 nucleocapsid-p1 cleavage site with a V82A drug-resistant mutation in viral protease.

Prabu-Jeyabalan M, Nalivaika EA, King NM, Schiffer CA. Prabu-Jeyabalan M, et al. J Virol. 2004 Nov;78(22):12446-54. doi: 10.1128/JVI.78.22.12446-12454.2004. J Virol. 2004. PMID: 15507631 Free PMC article.

8

Substrate envelope and drug resistance: crystal structure of RO1 in complex with wild-type human immunodeficiency virus type 1 protease.

Prabu-Jeyabalan M, King NM, Nalivaika EA, Heilek-Snyder G, Cammack N, Schiffer CA. Prabu-Jeyabalan M, et al. Antimicrob Agents Chemother. 2006 Apr;50(4):1518-21. doi: 10.1128/AAC.50.4.1518-1521.2006. Antimicrob Agents Chemother. 2006. PMID: 16569872 Free PMC article.

9

Extreme entropy-enthalpy compensation in a drug-resistant variant of HIV-1 protease.

King NM, Prabu-Jeyabalan M, Bandaranayake RM, Nalam MN, Nalivaika EA, Özen A, Haliloğlu T, Yilmaz NK, Schiffer CA. King NM, et al. Among authors: prabu jeyabalan m. ACS Chem Biol. 2012 Sep 21;7(9):1536-46. doi: 10.1021/cb300191k. Epub 2012 Jul 2. ACS Chem Biol. 2012. PMID: 22712830 Free PMC article.

10

Structural and thermodynamic basis of amprenavir/darunavir and atazanavir resistance in HIV-1 protease with mutations at residue 50.

Mittal S, Bandaranayake RM, King NM, Prabu-Jeyabalan M, Nalam MN, Nalivaika EA, Yilmaz NK, Schiffer CA. Mittal S, et al. Among authors: prabu jeyabalan m. J Virol. 2013 Apr;87(8):4176-84. doi: 10.1128/JVI.03486-12. Epub 2013 Jan 30. J Virol. 2013. PMID: 23365446 Free PMC article.

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