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Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory B-cells against other arthritogenic alphaviruses predominantly through the B domain of the E2 glycoprotein.
Powers JM, Lyski ZL, Weber WC, Denton M, Streblow MM, Mayo AT, Haese NN, Nix CD, Rodríguez-Santiago R, Alvarado LI, Rivera-Amill V, Messer WB, Streblow DN. Powers JM, et al. PLoS Negl Trop Dis. 2023 Mar 13;17(3):e0011154. doi: 10.1371/journal.pntd.0011154. eCollection 2023 Mar. PLoS Negl Trop Dis. 2023. PMID: 36913428 Free PMC article.
Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease.
Broeckel RM, Haese N, Ando T, Dmitriev I, Kreklywich CN, Powers J, Denton M, Smith P, Morrison TE, Heise M, DeFilippis V, Messaoudi I, Curiel DT, Streblow DN. Broeckel RM, et al. Front Immunol. 2019 Oct 31;10:2563. doi: 10.3389/fimmu.2019.02563. eCollection 2019. Front Immunol. 2019. PMID: 31736977 Free PMC article.
Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses.
Powers JM, Haese NN, Denton M, Ando T, Kreklywich C, Bonin K, Streblow CE, Kreklywich N, Smith P, Broeckel R, DeFilippis V, Morrison TE, Heise MT, Streblow DN. Powers JM, et al. PLoS Negl Trop Dis. 2021 Apr 1;15(4):e0009308. doi: 10.1371/journal.pntd.0009308. eCollection 2021 Apr. PLoS Negl Trop Dis. 2021. PMID: 33793555 Free PMC article.
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Kim J, Sprouse KR, Adams LE, Sundaramurthy S, Zhu X, Shirreff LM, Mallory ML, Scobey TD, Moreno A, O'Hagan DT, Kleanthous H, Villinger FJ, Veesler D, King NP, Suthar MS, Khurana S, Baric RS, Wilson IA, Pulendran B. Feng Y, et al. Among authors: powers jm. Sci Transl Med. 2023 May 10;15(695):eadg7404. doi: 10.1126/scitranslmed.adg7404. Epub 2023 May 10. Sci Transl Med. 2023. PMID: 37163615 Free PMC article.
A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
Tse LV, Hou YJ, McFadden E, Lee RE, Scobey TD, Leist SR, Martinez DR, Meganck RM, Schäfer A, Yount BL, Mascenik T, Powers JM, Randell SH, Zhang Y, Wang L, Mascola J, McLellan JS, Baric RS. Tse LV, et al. Among authors: powers jm. Sci Transl Med. 2023 Sep 27;15(715):eadg5567. doi: 10.1126/scitranslmed.adg5567. Epub 2023 Sep 27. Sci Transl Med. 2023. PMID: 37756379
Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus.
Dillard JA, Taft-Benz SA, Knight AC, Anderson EJ, Pressey KD, Parotti B, Martinez SA, Diaz JL, Sarkar S, Madden EA, De la Cruz G, Adams LE, Dinnon KH 3rd, Leist SR, Martinez DR, Schäfer A, Powers JM, Yount BL Jr, Castillo IN, Morales NL, Burdick J, Evangelista MKD, Ralph LM, Pankow NC, Linnertz CL, Lakshmanane P, Montgomery SA, Ferris MT, Baric RS, Baxter VK, Heise MT. Dillard JA, et al. Among authors: powers jm. Nat Commun. 2024 May 3;15(1):3738. doi: 10.1038/s41467-024-47450-x. Nat Commun. 2024. PMID: 38702297 Free PMC article.
722 results