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Human recombinant lysosomal enzymes produced in microorganisms.
Espejo-Mojica ÁJ, Alméciga-Díaz CJ, Rodríguez A, Mosquera Á, Díaz D, Beltrán L, Díaz S, Pimentel N, Moreno J, Sánchez J, Sánchez OF, Córdoba H, Poutou-Piñales RA, Barrera LA. Espejo-Mojica ÁJ, et al. Mol Genet Metab. 2015 Sep-Oct;116(1-2):13-23. doi: 10.1016/j.ymgme.2015.06.001. Epub 2015 Jun 6. Mol Genet Metab. 2015. PMID: 26071627 Review.
Plackett-Burman Design for rGILCC1 Laccase Activity Enhancement in Pichia pastoris: Concentrated Enzyme Kinetic Characterization.
Morales-Álvarez ED, Rivera-Hoyos CM, Cardozo-Bernal ÁM, Poutou-Piñales RA, Pedroza-Rodríguez AM, Díaz-Rincón DJ, Rodríguez-López A, Alméciga-Díaz CJ, Cuervo-Patiño CL. Morales-Álvarez ED, et al. Enzyme Res. 2017;2017:5947581. doi: 10.1155/2017/5947581. Epub 2017 Mar 21. Enzyme Res. 2017. PMID: 28421142 Free PMC article.
Production and characterization of a human lysosomal recombinant iduronate-2-sulfatase produced in Pichia pastoris.
Pimentel N, Rodríguez-Lopez A, Díaz S, Losada JC, Díaz-Rincón DJ, Cardona C, Espejo-Mojica ÁJ, Ramírez AM, Ruiz F, Landázuri P, Poutou-Piñales RA, Cordoba-Ruiz HA, Alméciga-Díaz CJ, Barrera-Avellaneda LA. Pimentel N, et al. Biotechnol Appl Biochem. 2018 Sep;65(5):655-664. doi: 10.1002/bab.1660. Epub 2018 Apr 23. Biotechnol Appl Biochem. 2018. PMID: 29633336
Media improvement for 10 L bioreactor production of rPOXA 1B laccase by P. pastoris.
Ardila-Leal LD, Albarracín-Pardo DA, Rivera-Hoyos CM, Morales-Álvarez ED, Poutou-Piñales RA, Cardozo-Bernal AM, Quevedo-Hidalgo BE, Pedroza-Rodríguez AM, Díaz-Rincón DJ, Rodríguez-López A, Alméciga-Díaz CJ, Cuervo-Patiño CL. Ardila-Leal LD, et al. 3 Biotech. 2019 Dec;9(12):447. doi: 10.1007/s13205-019-1979-y. Epub 2019 Nov 11. 3 Biotech. 2019. PMID: 31763125 Free PMC article.
Computational analysis and low-scale constitutive expression of laccases synthetic genes GlLCC1 from Ganoderma lucidum and POXA 1B from Pleurotus ostreatus in Pichia pastoris.
Rivera-Hoyos CM, Morales-Álvarez ED, Poveda-Cuevas SA, Reyes-Guzmán EA, Poutou-Piñales RA, Reyes-Montaño EA, Pedroza-Rodríguez AM, Rodríguez-Vázquez R, Cardozo-Bernal ÁM. Rivera-Hoyos CM, et al. PLoS One. 2015 Jan 22;10(1):e0116524. doi: 10.1371/journal.pone.0116524. eCollection 2015. PLoS One. 2015. PMID: 25611746 Free PMC article.
37 results