Potts MB - Search Results

1

Using functional signature ontology (FUSION) to identify mechanisms of action for natural products.

Potts MB, Kim HS, Fisher KW, Hu Y, Carrasco YP, Bulut GB, Ou YH, Herrera-Herrera ML, Cubillos F, Mendiratta S, Xiao G, Hofree M, Ideker T, Xie Y, Huang LJ, Lewis RE, MacMillan JB, White MA. Potts MB, et al. Sci Signal. 2013 Oct 15;6(297):ra90. doi: 10.1126/scisignal.2004657. Sci Signal. 2013. PMID: 24129700 Free PMC article.

2

A Genome-wide Functional Signature Ontology Map and Applications to Natural Product Mechanism of Action Discovery.

McMillan EA, Kwon G, Clemenceau JR, Fisher KW, Vaden RM, Shaikh AF, Neilsen BK, Kelly D, Potts MB, Sung YJ, Mendiratta S, Hight SK, Lee Y, MacMillan JB, Lewis RE, Kim HS, White MA. McMillan EA, et al. Among authors: potts mb. Cell Chem Biol. 2019 Oct 17;26(10):1380-1392.e6. doi: 10.1016/j.chembiol.2019.07.008. Epub 2019 Aug 1. Cell Chem Biol. 2019. PMID: 31378711 Free PMC article.

3

Discoipyrroles A-D: isolation, structure determination, and synthesis of potent migration inhibitors from Bacillus hunanensis.

Hu Y, Potts MB, Colosimo D, Herrera-Herrera ML, Legako AG, Yousufuddin M, White MA, MacMillan JB. Hu Y, et al. Among authors: potts mb. J Am Chem Soc. 2013 Sep 11;135(36):13387-92. doi: 10.1021/ja403412y. Epub 2013 Aug 28. J Am Chem Soc. 2013. PMID: 23984625 Free PMC article.

4

Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B.

Potts MB, McMillan EA, Rosales TI, Kim HS, Ou YH, Toombs JE, Brekken RA, Minden MD, MacMillan JB, White MA. Potts MB, et al. Nat Chem Biol. 2015 Jun;11(6):401-8. doi: 10.1038/nchembio.1797. Epub 2015 Apr 13. Nat Chem Biol. 2015. PMID: 25867045 Free PMC article.

5

FUSION-Guided Hypothesis Development Leads to the Identification of N⁶,N⁶-Dimethyladenosine, a Marine-Derived AKT Pathway Inhibitor.

Vaden RM, Oswald NW, Potts MB, MacMillan JB, White MA. Vaden RM, et al. Among authors: potts mb. Mar Drugs. 2017 Mar 15;15(3):75. doi: 10.3390/md15030075. Mar Drugs. 2017. PMID: 28294973 Free PMC article.

6

Degradation of AMPK by a cancer-specific ubiquitin ligase.

Pineda CT, Ramanathan S, Fon Tacer K, Weon JL, Potts MB, Ou YH, White MA, Potts PR. Pineda CT, et al. Among authors: potts mb, potts pr. Cell. 2015 Feb 12;160(4):715-728. doi: 10.1016/j.cell.2015.01.034. Cell. 2015. PMID: 25679763 Free PMC article.

7

A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression.

Shields BB, Pecot CV, Gao H, McMillan E, Potts M, Nagel C, Purinton S, Wang Y, Ivan C, Kim HS, Borkowski RJ, Khan S, Rodriguez-Aguayo C, Lopez-Berestein G, Lea J, Gazdar A, Baggerly KA, Sood AK, White MA. Shields BB, et al. Mol Syst Biol. 2015 Dec 11;11(12):842. doi: 10.15252/msb.20156308. Mol Syst Biol. 2015. PMID: 26655797 Free PMC article.

8

Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening.

Piala AT, Akella R, Potts MB, Dudics-Giagnocavo SA, He H, Wei S, White MA, Posner BA, Goldsmith EJ. Piala AT, et al. Among authors: potts mb. Bioorg Med Chem Lett. 2016 Aug 15;26(16):3923-7. doi: 10.1016/j.bmcl.2016.07.016. Epub 2016 Jul 6. Bioorg Med Chem Lett. 2016. PMID: 27426302

9

MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation.

Craig JE, Miller JN, Rayavarapu RR, Hong Z, Bulut GB, Zhuang W, Sakurada SM, Temirov J, Low JA, Chen T, Pruett-Miller SM, Huang LJ, Potts MB. Craig JE, et al. Among authors: potts mb. Cell Death Discov. 2020 Oct 20;6:107. doi: 10.1038/s41420-020-00342-7. eCollection 2020. Cell Death Discov. 2020. PMID: 33101709 Free PMC article.

10

Cell lineage and cell death: Caenorhabditis elegans and cancer research.

Potts MB, Cameron S. Potts MB, et al. Nat Rev Cancer. 2011 Jan;11(1):50-8. doi: 10.1038/nrc2984. Epub 2010 Dec 2. Nat Rev Cancer. 2011. PMID: 21150934 Review.

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