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An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia.
Xie H, Heier C, Meng X, Bakiri L, Pototschnig I, Tang Z, Schauer S, Baumgartner VJ, Grabner GF, Schabbauer G, Wolinski H, Robertson GR, Hoefler G, Zeng W, Wagner EF, Schweiger M, Zechner R. Xie H, et al. Among authors: pototschnig i. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2112840119. doi: 10.1073/pnas.2112840119. Proc Natl Acad Sci U S A. 2022. PMID: 35210363 Free PMC article.
Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Pajed L, Taschler U, Tilp A, Hofer P, Kotzbeck P, Kolleritsch S, Radner FPW, Pototschnig I, Wagner C, Schratter M, Eder S, Huetter S, Schreiber R, Haemmerle G, Eichmann TO, Schweiger M, Hoefler G, Kershaw EE, Lass A, Schoiswohl G. Pajed L, et al. Among authors: pototschnig i. Commun Biol. 2021 Mar 10;4(1):323. doi: 10.1038/s42003-021-01858-z. Commun Biol. 2021. PMID: 33692445 Free PMC article.
Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
Pajed L, Wagner C, Taschler U, Schreiber R, Kolleritsch S, Fawzy N, Pototschnig I, Schoiswohl G, Pusch LM, Wieser BI, Vesely P, Hoefler G, Eichmann TO, Zimmermann R, Lass A. Pajed L, et al. Among authors: pototschnig i. J Biol Chem. 2019 Jun 7;294(23):9118-9133. doi: 10.1074/jbc.RA118.007201. Epub 2019 Apr 25. J Biol Chem. 2019. PMID: 31023823 Free PMC article.
R-ketorolac ameliorates cancer-associated cachexia and prolongs survival of tumour-bearing mice.
Chrysostomou SE, Eder S, Pototschnig I, Mayer AL, Derler M, Mussbacher M, Schauer S, Zhang D, Yan D, Liu G, Hoefler G, Weichhart T, Vesely PW, Zhang L, Schweiger M. Chrysostomou SE, et al. Among authors: pototschnig i. J Cachexia Sarcopenia Muscle. 2024 Apr;15(2):562-574. doi: 10.1002/jcsm.13422. Epub 2024 Feb 1. J Cachexia Sarcopenia Muscle. 2024. PMID: 38302863 Free PMC article.
Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia.
Pototschnig I, Feiler U, Diwoky C, Vesely PW, Rauchenwald T, Paar M, Bakiri L, Pajed L, Hofer P, Kashofer K, Sukhbaatar N, Schoiswohl G, Weichhart T, Hoefler G, Bock C, Pichler M, Wagner EF, Zechner R, Schweiger M. Pototschnig I, et al. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):93-107. doi: 10.1002/jcsm.13109. Epub 2022 Nov 9. J Cachexia Sarcopenia Muscle. 2023. PMID: 36351437 Free PMC article.