Potęga A - Search Results

1

pH-Responsive Drug Delivery Nanoplatforms as Smart Carriers of Unsymmetrical Bisacridines for Targeted Cancer Therapy.

Pilch J, Potęga A, Kowalczyk A, Kasprzak A, Kowalik P, Bujak P, Paluszkiewicz E, Augustin E, Nowicka AM. Pilch J, et al. Among authors: potega a. Pharmaceutics. 2023 Jan 6;15(1):201. doi: 10.3390/pharmaceutics15010201. Pharmaceutics. 2023. PMID: 36678830 Free PMC article.

2

Diminished toxicity of C-1748, 4-methyl-9-hydroxyethylamino-1-nitroacridine, compared with its demethyl analog, C-857, corresponds to its resistance to metabolism in HepG2 cells.

Wiśniewska A, Niemira M, Jagiełło K, Potęga A, Swist M, Henderson C, Skwarska A, Augustin E, Konopa J, Mazerska Z. Wiśniewska A, et al. Among authors: potega a. Biochem Pharmacol. 2012 Jul 1;84(1):30-42. doi: 10.1016/j.bcp.2012.03.013. Epub 2012 Apr 6. Biochem Pharmacol. 2012. PMID: 22484277

3

Modulation of CYP3A4 activity and induction of apoptosis, necrosis and senescence by the anti-tumour imidazoacridinone C-1311 in human hepatoma cells.

Augustin E, Pawłowska M, Polewska J, Potega A, Mazerska Z. Augustin E, et al. Among authors: potega a. Cell Biol Int. 2013 Feb;37(2):109-20. doi: 10.1002/cbin.10018. Epub 2013 Jan 14. Cell Biol Int. 2013. PMID: 23319370

4

Phase I and phase II metabolism simulation of antitumor-active 2-hydroxyacridinone with electrochemistry coupled on-line with mass spectrometry.

Potęga A, Garwolińska D, Nowicka AM, Fau M, Kot-Wasik A, Mazerska Z. Potęga A, et al. Xenobiotica. 2019 Aug;49(8):922-934. doi: 10.1080/00498254.2018.1524946. Epub 2019 Jan 4. Xenobiotica. 2019. PMID: 30301406

5

Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053.

Potęga A, Paczkowski S, Paluszkiewicz E, Mazerska Z. Potęga A, et al. J Pharm Biomed Anal. 2021 Apr 15;197:113970. doi: 10.1016/j.jpba.2021.113970. Epub 2021 Feb 13. J Pharm Biomed Anal. 2021. PMID: 33618132

6

Metabolic Profiles of New Unsymmetrical Bisacridine Antitumor Agents in Electrochemical and Enzymatic Noncellular Systems and in Tumor Cells.

Mieszkowska A, Nowicka AM, Kowalczyk A, Potęga A, Pawłowska M, Kosno M, Augustin E, Mazerska Z. Mieszkowska A, et al. Among authors: potega a. Pharmaceuticals (Basel). 2021 Apr 1;14(4):317. doi: 10.3390/ph14040317. Pharmaceuticals (Basel). 2021. PMID: 33915981 Free PMC article.

7

New, fast and cheap prediction tests for BRCA1 gene mutations identification in clinical samples.

Gajda-Walczak A, Potęga A, Kowalczyk A, Sek S, Zięba S, Kowalik A, Kudelski A, Nowicka AM. Gajda-Walczak A, et al. Among authors: potega a. Sci Rep. 2023 May 5;13(1):7316. doi: 10.1038/s41598-023-34588-9. Sci Rep. 2023. PMID: 37147448 Free PMC article.

8

Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity.

Potęga A, Göldner V, Niehaves E, Paluszkiewicz E, Karst U. Potęga A, et al. J Pharm Biomed Anal. 2023 Oct 25;235:115607. doi: 10.1016/j.jpba.2023.115607. Epub 2023 Jul 26. J Pharm Biomed Anal. 2023. PMID: 37523868

9

In Vitro Enzyme Kinetics and NMR-Based Product Elucidation for Glutathione S-Conjugation of the Anticancer Unsymmetrical Bisacridine C-2028 in Liver Microsomes and Cytosol: Major Role of Glutathione S-Transferase M1-1 Isoenzyme.

Potęga A, Rafalska D, Kazimierczyk D, Kosno M, Pawłowicz A, Andrałojć W, Paluszkiewicz E, Laskowski T. Potęga A, et al. Molecules. 2023 Sep 26;28(19):6812. doi: 10.3390/molecules28196812. Molecules. 2023. PMID: 37836655 Free PMC article.

10

Acid-Base Equilibrium and Self-Association in Relation to High Antitumor Activity of Selected Unsymmetrical Bisacridines Established by Extensive Chemometric Analysis.

Kosno M, Laskowski T, Frackowiak JE, Potęga A, Kurdyn A, Andrałojć W, Borzyszkowska-Bukowska J, Szwarc-Karabyka K, Mazerska Z. Kosno M, et al. Among authors: potega a. Molecules. 2022 Jun 21;27(13):3995. doi: 10.3390/molecules27133995. Molecules. 2022. PMID: 35807234 Free PMC article.

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