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Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on an IL23/IFNγ axis.
Lo JW, Cozzetto D, Alexander JL, Danckert NP, Madgwick M, Knox N, Sieh JYX, Olbei M, Liu Z, Ibraheim H, Blanco JM, Kudo H, Seoane RC, Possamai LA, Goldin R, Marchesi J, Korcsmaros T, Lord GM, Powell N. Lo JW, et al. Among authors: possamai la. Nat Commun. 2023 Oct 23;14(1):6719. doi: 10.1038/s41467-023-41798-2. Nat Commun. 2023. PMID: 37872166 Free PMC article.
Character and temporal evolution of apoptosis in acetaminophen-induced acute liver failure*.
Possamai LA, McPhail MJ, Quaglia A, Zingarelli V, Abeles RD, Tidswell R, Puthucheary Z, Rawal J, Karvellas CJ, Leslie EM, Hughes RD, Ma Y, Jassem W, Shawcross DL, Bernal W, Dharwan A, Heaton ND, Thursz M, Wendon JA, Mitry RR, Antoniades CG. Possamai LA, et al. Crit Care Med. 2013 Nov;41(11):2543-50. doi: 10.1097/CCM.0b013e31829791a2. Crit Care Med. 2013. PMID: 23949472 Free PMC article.
Retinoic Acid Receptor-β Is Downregulated in Hepatocellular Carcinoma and Cirrhosis and Its Expression Inhibits Myosin-Driven Activation and Durotaxis in Hepatic Stellate Cells.
Cortes E, Lachowski D, Rice A, Chronopoulos A, Robinson B, Thorpe S, Lee DA, Possamai LA, Wang H, Pinato DJ, Del Río Hernández AE. Cortes E, et al. Among authors: possamai la. Hepatology. 2019 Feb;69(2):785-802. doi: 10.1002/hep.30193. Epub 2018 Dec 17. Hepatology. 2019. PMID: 30055117 Free article.
PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury.
Triantafyllou E, Gudd CL, Mawhin MA, Husbyn HC, Trovato FM, Siggins MK, O'Connor T, Kudo H, Mukherjee SK, Wendon JA, Bernsmeier C, Goldin RD, Botto M, Khamri W, McPhail MJ, Possamai LA, Woollard KJ, Antoniades CG, Thursz MR. Triantafyllou E, et al. Among authors: possamai la. J Clin Invest. 2021 Feb 15;131(4):e140196. doi: 10.1172/JCI140196. J Clin Invest. 2021. PMID: 33320839 Free PMC article.
Activation and transcriptional profile of monocytes and CD8+ T cells are altered in checkpoint inhibitor-related hepatitis.
Gudd CLC, Au L, Triantafyllou E, Shum B, Liu T, Nathwani R, Kumar N, Mukherjee S, Dhar A, Woollard KJ, Yone Y, Pinato DJ, Thursz MR, Goldin RD, Gore ME, Larkin J, Khamri W, Antoniades CG, Turajlic S, Possamai LA. Gudd CLC, et al. Among authors: possamai la. J Hepatol. 2021 Jul;75(1):177-189. doi: 10.1016/j.jhep.2021.02.008. Epub 2021 Feb 22. J Hepatol. 2021. PMID: 33631227 Free article.
28 results