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Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications.
Lopes M, Duarte TL, Teles MJ, Mosteo L, Chacim S, Aguiar E, Pereira-Reis J, Oliveira M, Silva AMN, Gonçalves N, Martins G, Kong IY, Zethoven M, Vervoort S, Martins S, Quintela M, Hawkins ED, Trigo F, Guimarães JT, Mariz JM, Porto G, Duarte D. Lopes M, et al. Among authors: porto g. Blood Adv. 2021 Aug 24;5(16):3102-3112. doi: 10.1182/bloodadvances.2021004373. Blood Adv. 2021. PMID: 34402883 Free PMC article.
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.
Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H. Pasricha SR, et al. Among authors: porto g. Nat Commun. 2017 Sep 1;8(1):403. doi: 10.1038/s41467-017-00500-z. Nat Commun. 2017. PMID: 28864822 Free PMC article.
Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.
Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H. Lim PJ, et al. Among authors: porto g. Nat Metab. 2019 May;1(5):519-531. doi: 10.1038/s42255-019-0063-6. Epub 2019 May 13. Nat Metab. 2019. PMID: 31276102 Free PMC article.
Ferritin Increase in Hemochromatosis Subjects After Discontinuing Their Regular Maintenance Treatment: A Longitudinal Analysis Performed During the COVID-19 Imposed Hospital Lockdown.
Coutinho MP, Teles MJ, Melo G, Lopes M, Duarte D, Duarte TL, Reis J, Martins AC, Oliveira JC, Porto G. Coutinho MP, et al. Among authors: porto g. Hemasphere. 2022 Aug 23;6(9):e770. doi: 10.1097/HS9.0000000000000770. eCollection 2022 Sep. Hemasphere. 2022. PMID: 36034093 Free PMC article. No abstract available.
333 results