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Gene targeting using zinc finger nucleases.
Porteus MH, Carroll D. Porteus MH, et al. Nat Biotechnol. 2005 Aug;23(8):967-73. doi: 10.1038/nbt1125. Nat Biotechnol. 2005. PMID: 16082368 Review.
Gene editing: not just for translation anymore.
McMahon MA, Rahdar M, Porteus M. McMahon MA, et al. Nat Methods. 2011 Dec 28;9(1):28-31. doi: 10.1038/nmeth.1811. Nat Methods. 2011. PMID: 22205513 No abstract available.
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells.
Dever DP, Bak RO, Reinisch A, Camarena J, Washington G, Nicolas CE, Pavel-Dinu M, Saxena N, Wilkens AB, Mantri S, Uchida N, Hendel A, Narla A, Majeti R, Weinberg KI, Porteus MH. Dever DP, et al. Among authors: porteus mh. Nature. 2016 Nov 17;539(7629):384-389. doi: 10.1038/nature20134. Epub 2016 Nov 7. Nature. 2016. PMID: 27820943 Free PMC article.
Efficient scarless genome editing in human pluripotent stem cells.
Ikeda K, Uchida N, Nishimura T, White J, Martin RM, Nakauchi H, Sebastiano V, Weinberg KI, Porteus MH. Ikeda K, et al. Among authors: porteus mh. Nat Methods. 2018 Dec;15(12):1045-1047. doi: 10.1038/s41592-018-0212-y. Epub 2018 Nov 30. Nat Methods. 2018. PMID: 30504872
Gene correction for SCID-X1 in long-term hematopoietic stem cells.
Pavel-Dinu M, Wiebking V, Dejene BT, Srifa W, Mantri S, Nicolas CE, Lee C, Bao G, Kildebeck EJ, Punjya N, Sindhu C, Inlay MA, Saxena N, DeRavin SS, Malech H, Roncarolo MG, Weinberg KI, Porteus MH. Pavel-Dinu M, et al. Among authors: porteus mh. Nat Commun. 2019 Apr 9;10(1):1634. doi: 10.1038/s41467-019-09614-y. Nat Commun. 2019. PMID: 30967552 Free PMC article.
Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.
de Alencastro G, Puzzo F, Pavel-Dinu M, Zhang F, Pillay S, Majzoub K, Tiffany M, Jang H, Sheikali A, Cromer MK, Meetei R, Carette JE, Porteus MH, Pekrun K, Kay MA. de Alencastro G, et al. Among authors: porteus mh. Mol Ther. 2021 Mar 3;29(3):1016-1027. doi: 10.1016/j.ymthe.2020.10.020. Epub 2020 Oct 22. Mol Ther. 2021. PMID: 33678249 Free PMC article.
178 results