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APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Tsiantoulas D, Eslami M, Obermayer G, Clement M, Smeets D, Mayer FJ, Kiss MG, Enders L, Weißer J, Göderle L, Lambert J, Frommlet F, Mueller A, Hendrikx T, Ozsvar-Kozma M, Porsch F, Willen L, Afonyushkin T, Murphy JE, Fogelstrand P, Donzé O, Pasterkamp G, Hoke M, Kubicek S, Jørgensen HF, Danchin N, Simon T, Scharnagl H, März W, Borén J, Hess H, Mallat Z, Schneider P, Binder CJ. Tsiantoulas D, et al. Among authors: porsch f. Nature. 2021 Sep;597(7874):92-96. doi: 10.1038/s41586-021-03818-3. Epub 2021 Aug 25. Nature. 2021. PMID: 34433968
B Cell-Activating Factor Neutralization Aggravates Atherosclerosis.
Tsiantoulas D, Sage AP, Göderle L, Ozsvar-Kozma M, Murphy D, Porsch F, Pasterkamp G, Menche J, Schneider P, Mallat Z, Binder CJ. Tsiantoulas D, et al. Among authors: porsch f. Circulation. 2018 Nov 13;138(20):2263-2273. doi: 10.1161/CIRCULATIONAHA.117.032790. Circulation. 2018. PMID: 29858401 Free PMC article.
Impact of B-Cell-Targeted Therapies on Cardiovascular Disease.
Porsch F, Binder CJ. Porsch F, et al. Arterioscler Thromb Vasc Biol. 2019 Sep;39(9):1705-1714. doi: 10.1161/ATVBAHA.119.311996. Epub 2019 Jul 18. Arterioscler Thromb Vasc Biol. 2019. PMID: 31315439 Free article. Review.
Soluble TREM2 levels reflect the recruitment and expansion of TREM2+ macrophages that localize to fibrotic areas and limit NASH.
Hendrikx T, Porsch F, Kiss MG, Rajcic D, Papac-Miličević N, Hoebinger C, Goederle L, Hladik A, Shaw LE, Horstmann H, Knapp S, Derdak S, Bilban M, Heintz L, Krawczyk M, Paternostro R, Trauner M, Farlik M, Wolf D, Binder CJ. Hendrikx T, et al. Among authors: porsch f. J Hepatol. 2022 Nov;77(5):1373-1385. doi: 10.1016/j.jhep.2022.06.004. Epub 2022 Jun 21. J Hepatol. 2022. PMID: 35750138 Free article.
Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis.
Kiss MG, Papac-Miličević N, Porsch F, Tsiantoulas D, Hendrikx T, Takaoka M, Dinh HQ, Narzt MS, Göderle L, Ozsvár-Kozma M, Schuster M, Fortelny N, Hladik A, Knapp S, Gruber F, Pickering MC, Bock C, Swirski FK, Ley K, Zernecke A, Cochain C, Kemper C, Mallat Z, Binder CJ. Kiss MG, et al. Among authors: porsch f. Immunity. 2023 Aug 8;56(8):1809-1824.e10. doi: 10.1016/j.immuni.2023.06.026. Epub 2023 Jul 26. Immunity. 2023. PMID: 37499656
Anti-inflammatory and Immunomodulatory Therapies in Atherosclerosis.
Deroissart J, Porsch F, Koller T, Binder CJ. Deroissart J, et al. Among authors: porsch f. 2021 Jul 13. In: von Eckardstein A, Binder CJ, editors. Prevention and Treatment of Atherosclerosis: Improving State-of-the-Art Management and Search for Novel Targets [Internet]. Cham (CH): Springer; 2022. 2021 Jul 13. In: von Eckardstein A, Binder CJ, editors. Prevention and Treatment of Atherosclerosis: Improving State-of-the-Art Management and Search for Novel Targets [Internet]. Cham (CH): Springer; 2022. PMID: 36122115 Free Books & Documents. Review.
18 results