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The Microbiology of Ruthenium Complexes.
Southam HM, Butler JA, Chapman JA, Poole RK. Southam HM, et al. Among authors: poole rk. Adv Microb Physiol. 2017;71:1-96. doi: 10.1016/bs.ampbs.2017.03.001. Epub 2017 May 29. Adv Microb Physiol. 2017. PMID: 28760320 Review.
A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3.
Southam HM, Smith TW, Lyon RL, Liao C, Trevitt CR, Middlemiss LA, Cox FL, Chapman JA, El-Khamisy SF, Hippler M, Williamson MP, Henderson PJF, Poole RK. Southam HM, et al. Among authors: poole rk. Redox Biol. 2018 Sep;18:114-123. doi: 10.1016/j.redox.2018.06.008. Epub 2018 Jun 30. Redox Biol. 2018. PMID: 30007887 Free PMC article.
CORM-3 induces DNA damage through Ru(II) binding to DNA.
Lyon RF, Southam HM, Trevitt CR, Liao C, El-Khamisy SF, Poole RK, Williamson MP. Lyon RF, et al. Among authors: poole rk. Biochem J. 2022 Jul 15;479(13):1429-1439. doi: 10.1042/BCJ20220254. Biochem J. 2022. PMID: 35726678 Free PMC article.
307 results