Polyak SW - Search Results

1

Short Photoswitchable Antibacterial Peptides.

Yeoh YQ, Horsley JR, Yu J, Polyak SW, Jovcevski B, Abell AD. Yeoh YQ, et al. Among authors: polyak sw. ChemMedChem. 2020 Aug 19;15(16):1505-1508. doi: 10.1002/cmdc.202000280. Epub 2020 Jul 7. ChemMedChem. 2020. PMID: 32558320

2

Structure, function and selective inhibition of bacterial acetyl-coa carboxylase.

Polyak SW, Abell AD, Wilce MC, Zhang L, Booker GW. Polyak SW, et al. Appl Microbiol Biotechnol. 2012 Feb;93(3):983-92. doi: 10.1007/s00253-011-3796-z. Epub 2011 Dec 20. Appl Microbiol Biotechnol. 2012. PMID: 22183085 Review.

3

Selective inhibition of biotin protein ligase from Staphylococcus aureus.

Soares da Costa TP, Tieu W, Yap MY, Pendini NR, Polyak SW, Sejer Pedersen D, Morona R, Turnidge JD, Wallace JC, Wilce MCJ, Booker GW, Abell AD. Soares da Costa TP, et al. Among authors: polyak sw. J Biol Chem. 2012 May 18;287(21):17823-17832. doi: 10.1074/jbc.M112.356576. Epub 2012 Mar 21. J Biol Chem. 2012. PMID: 22437830 Free PMC article.

4

5-benzylidenerhodanine and 5-benzylidene-2-4-thiazolidinedione based antibacterials.

Zvarec O, Polyak SW, Tieu W, Kuan K, Dai H, Pedersen DS, Morona R, Zhang L, Booker GW, Abell AD. Zvarec O, et al. Among authors: polyak sw. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2720-2. doi: 10.1016/j.bmcl.2012.02.100. Epub 2012 Mar 6. Bioorg Med Chem Lett. 2012. PMID: 22444680

5

Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: an antibiotic target.

Pendini NR, Yap MY, Traore DA, Polyak SW, Cowieson NP, Abell A, Booker GW, Wallace JC, Wilce JA, Wilce MC. Pendini NR, et al. Among authors: polyak sw. Protein Sci. 2013 Jun;22(6):762-73. doi: 10.1002/pro.2262. Protein Sci. 2013. PMID: 23559560 Free PMC article.

6

Structure guided design of biotin protein ligase inhibitors for antibiotic discovery.

Paparella AS, Soares da Costa TP, Yap MY, Tieu W, Wilce MC, Booker GW, Abell AD, Polyak SW. Paparella AS, et al. Among authors: polyak sw. Curr Top Med Chem. 2014;14(1):4-20. doi: 10.2174/1568026613666131111103149. Curr Top Med Chem. 2014. PMID: 24236729 Review.

7

Dual roles of F123 in protein homodimerization and inhibitor binding to biotin protein ligase from Staphylococcus aureus.

Soares da Costa TP, Yap MY, Perugini MA, Wallace JC, Abell AD, Wilce MC, Polyak SW, Booker GW. Soares da Costa TP, et al. Among authors: polyak sw. Mol Microbiol. 2014 Jan;91(1):110-20. doi: 10.1111/mmi.12446. Epub 2013 Nov 21. Mol Microbiol. 2014. PMID: 24261685 Free article.

8

Biotin analogues with antibacterial activity are potent inhibitors of biotin protein ligase.

Soares da Costa TP, Tieu W, Yap MY, Zvarec O, Bell JM, Turnidge JD, Wallace JC, Booker GW, Wilce MC, Abell AD, Polyak SW. Soares da Costa TP, et al. Among authors: polyak sw. ACS Med Chem Lett. 2012 May 23;3(6):509-14. doi: 10.1021/ml300106p. eCollection 2012 Jun 14. ACS Med Chem Lett. 2012. PMID: 24900501 Free PMC article.

9

Heterocyclic acyl-phosphate bioisostere-based inhibitors of Staphylococcus aureus biotin protein ligase.

Tieu W, Jarrad AM, Paparella AS, Keeling KA, Soares da Costa TP, Wallace JC, Booker GW, Polyak SW, Abell AD. Tieu W, et al. Among authors: polyak sw. Bioorg Med Chem Lett. 2014 Oct 1;24(19):4689-4693. doi: 10.1016/j.bmcl.2014.08.030. Epub 2014 Aug 19. Bioorg Med Chem Lett. 2014. PMID: 25193234

10

Improved Synthesis of Biotinol-5'-AMP: Implications for Antibacterial Discovery.

Tieu W, Polyak SW, Paparella AS, Yap MY, Soares da Costa TP, Ng B, Wang G, Lumb R, Bell JM, Turnidge JD, Wilce MC, Booker GW, Abell AD. Tieu W, et al. Among authors: polyak sw. ACS Med Chem Lett. 2014 Dec 11;6(2):216-20. doi: 10.1021/ml500475n. eCollection 2015 Feb 12. ACS Med Chem Lett. 2014. PMID: 25699152 Free PMC article.

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