Plouffe B - Search Results

1

Constitutive activities and inverse agonism in dopamine receptors.

Zhang B, Albaker A, Plouffe B, Lefebvre C, Tiberi M. Zhang B, et al. Among authors: plouffe b. Adv Pharmacol. 2014;70:175-214. doi: 10.1016/B978-0-12-417197-8.00007-9. Adv Pharmacol. 2014. PMID: 24931197 Review.

2

Probing the constitutive activity among dopamine D1 and D5 receptors and their mutants.

Plouffe B, D'Aoust JP, Laquerre V, Liang B, Tiberi M. Plouffe B, et al. Methods Enzymol. 2010;484:295-328. doi: 10.1016/B978-0-12-381298-8.00016-2. Methods Enzymol. 2010. PMID: 21036239

3

The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner.

Plouffe B, Yang X, Tiberi M. Plouffe B, et al. Cell Signal. 2012 Jan;24(1):106-18. doi: 10.1016/j.cellsig.2011.08.008. Epub 2011 Aug 26. Cell Signal. 2012. PMID: 21893192

4

Functional analysis of human D1 and D5 dopaminergic G protein-coupled receptors: lessons from mutagenesis of a conserved serine residue in the cytosolic end of transmembrane region 6.

Plouffe B, Tiberi M. Plouffe B, et al. Methods Mol Biol. 2013;964:141-80. doi: 10.1007/978-1-62703-251-3_10. Methods Mol Biol. 2013. PMID: 23296783

5

Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure.

Möller D, Banerjee A, Uzuneser TC, Skultety M, Huth T, Plouffe B, Hübner H, Alzheimer C, Friedland K, Müller CP, Bouvier M, Gmeiner P. Möller D, et al. Among authors: plouffe b. J Med Chem. 2017 Apr 13;60(7):2908-2929. doi: 10.1021/acs.jmedchem.6b01857. Epub 2017 Mar 22. J Med Chem. 2017. PMID: 28248104

6

Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis.

Cahill TJ 3rd, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J 4th, Antar A, Blanc A, Qu CX, Chen X, Kawakami K, Inoue A, Aoki J, Steyaert J, Sun JP, Bouvier M, Skiniotis G, Lefkowitz RJ. Cahill TJ 3rd, et al. Among authors: plouffe b. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2562-2567. doi: 10.1073/pnas.1701529114. Epub 2017 Feb 21. Proc Natl Acad Sci U S A. 2017. PMID: 28223524 Free PMC article.

7

Purinergic Receptor Transactivation by the β₂-Adrenergic Receptor Increases Intracellular Ca²⁺ in Nonexcitable Cells.

Stallaert W, van der Westhuizen ET, Schönegge AM, Plouffe B, Hogue M, Lukashova V, Inoue A, Ishida S, Aoki J, Le Gouill C, Bouvier M. Stallaert W, et al. Among authors: plouffe b. Mol Pharmacol. 2017 May;91(5):533-544. doi: 10.1124/mol.116.106419. Epub 2017 Mar 9. Mol Pharmacol. 2017. PMID: 28280061

8

Michaelis-Menten Quantification of Ligand Signaling Bias Applied to the Promiscuous Vasopressin V2 Receptor.

Heydenreich FM, Plouffe B, Rizk A, Milić D, Zhou J, Breton B, Le Gouill C, Inoue A, Bouvier M, Veprintsev DB. Heydenreich FM, et al. Among authors: plouffe b. Mol Pharmacol. 2022 Sep;102(3):139-149. doi: 10.1124/molpharm.122.000497. Epub 2022 Jul 2. Mol Pharmacol. 2022. PMID: 35779859

9

New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists.

Rosenström U, Sköld C, Plouffe B, Beaudry H, Lindeberg G, Botros M, Nyberg F, Wolf G, Karlén A, Gallo-Payet N, Hallberg A. Rosenström U, et al. Among authors: plouffe b. J Med Chem. 2005 Jun 16;48(12):4009-24. doi: 10.1021/jm0491492. J Med Chem. 2005. PMID: 15943474

10

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation.

Brouwers B, de Oliveira EM, Marti-Solano M, Monteiro FBF, Laurin SA, Keogh JM, Henning E, Bounds R, Daly CA, Houston S, Ayinampudi V, Wasiluk N, Clarke D, Plouffe B, Bouvier M, Babu MM, Farooqi IS, Mokrosiński J. Brouwers B, et al. Among authors: plouffe b. Cell Rep. 2021 Mar 23;34(12):108862. doi: 10.1016/j.celrep.2021.108862. Cell Rep. 2021. PMID: 33761344 Free PMC article.

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