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Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease.
Park JS, Kam TI, Lee S, Park H, Oh Y, Kwon SH, Song JJ, Kim D, Kim H, Jhaldiyal A, Na DH, Lee KC, Park EJ, Pomper MG, Pletnikova O, Troncoso JC, Ko HS, Dawson VL, Dawson TM, Lee S. Park JS, et al. Among authors: pletnikova o. Acta Neuropathol Commun. 2021 Apr 26;9(1):78. doi: 10.1186/s40478-021-01180-z. Acta Neuropathol Commun. 2021. PMID: 33902708 Free PMC article.
Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Li W, West N, Colla E, Pletnikova O, Troncoso JC, Marsh L, Dawson TM, Jäkälä P, Hartmann T, Price DL, Lee MK. Li W, et al. Among authors: pletnikova o. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2162-7. doi: 10.1073/pnas.0406976102. Epub 2005 Jan 31. Proc Natl Acad Sci U S A. 2005. PMID: 15684072 Free PMC article.
Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.
Ko HS, von Coelln R, Sriram SR, Kim SW, Chung KK, Pletnikova O, Troncoso J, Johnson B, Saffary R, Goh EL, Song H, Park BJ, Kim MJ, Kim S, Dawson VL, Dawson TM. Ko HS, et al. Among authors: pletnikova o. J Neurosci. 2005 Aug 31;25(35):7968-78. doi: 10.1523/JNEUROSCI.2172-05.2005. J Neurosci. 2005. PMID: 16135753 Free PMC article.
Resistance to Alzheimer's pathology is associated with nuclear hypertrophy in neurons.
Riudavets MA, Iacono D, Resnick SM, O'Brien R, Zonderman AB, Martin LJ, Rudow G, Pletnikova O, Troncoso JC. Riudavets MA, et al. Among authors: o brien r, pletnikova o. Neurobiol Aging. 2007 Oct;28(10):1484-92. doi: 10.1016/j.neurobiolaging.2007.05.005. Epub 2007 Jun 28. Neurobiol Aging. 2007. PMID: 17599696 Free PMC article.
130 results