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4'-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication.
Sourimant J, Lieber CM, Aggarwal M, Cox RM, Wolf JD, Yoon JJ, Toots M, Ye C, Sticher Z, Kolykhalov AA, Martinez-Sobrido L, Bluemling GR, Natchus MG, Painter GR, Plemper RK. Sourimant J, et al. Among authors: plemper rk. Science. 2022 Jan 14;375(6577):161-167. doi: 10.1126/science.abj5508. Epub 2021 Dec 2. Science. 2022. PMID: 34855509 Free PMC article.
2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.
Kuhn JH, Adkins S, Alkhovsky SV, Avšič-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Bandte M, Beer M, Bejerman N, Bergeron É, Biedenkopf N, Bigarré L, Blair CD, Blasdell KR, Bradfute SB, Briese T, Brown PA, Bruggmann R, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Büttner C, Calisher CH, Candresse T, Carson J, Casas I, Chandran K, Charrel RN, Chiaki Y, Crane A, Crane M, Dacheux L, Bó ED, de la Torre JC, de Lamballerie X, de Souza WM, de Swart RL, Dheilly NM, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Drexler JF, Duprex WP, Dürrwald R, Easton AJ, Elbeaino T, Ergünay K, Feng G, Feuvrier C, Firth AE, Fooks AR, Formenty PBH, Freitas-Astúa J, Gago-Zachert S, García ML, García-Sastre A, Garrison AR, Godwin SE, Gonzalez JJ, de Bellocq JG, Griffiths A, Groschup MH, Günther S, Hammond J, Hepojoki J, Hierweger MM, Hongō S, Horie M, Horikawa H, Hughes HR, Hume AJ, Hyndman TH, Jiāng D, Jonson GB, Junglen S, Kadono F, Karlin DG, Klempa B, Klingström J, Koch MC, Kondō H, Koonin EV, Krásová J, Krupovic M, Kubota K, Kuzmin IV, Laenen L, Lambert AJ, Lǐ J, Li JM, Lieffrig F, Lukashevich IS, Luo D, Maes P, Marklewitz M, Marshall SH, Marzano SL, McCauley JW, Mirazimi A, Mohr… See abstract for full author list ➔ Kuhn JH, et al. Among authors: plemper rk. Arch Virol. 2022 Dec;167(12):2857-2906. doi: 10.1007/s00705-022-05546-z. Arch Virol. 2022. PMID: 36437428 Free PMC article.
Nonpeptide inhibitors of measles virus entry.
Sun A, Prussia A, Zhan W, Murray EE, Doyle J, Cheng LT, Yoon JJ, Radchenko EV, Palyulin VA, Compans RW, Liotta DC, Plemper RK, Snyder JP. Sun A, et al. Among authors: plemper rk. J Med Chem. 2006 Aug 24;49(17):5080-92. doi: 10.1021/jm0602559. J Med Chem. 2006. PMID: 16913698
High-throughput screening-based identification of paramyxovirus inhibitors.
Yoon JJ, Chawla D, Paal T, Ndungu M, Du Y, Kurtkaya S, Sun A, Snyder JP, Plemper RK. Yoon JJ, et al. Among authors: plemper rk. J Biomol Screen. 2008 Aug;13(7):591-608. doi: 10.1177/1087057108321089. Epub 2008 Jul 14. J Biomol Screen. 2008. PMID: 18626114 Free PMC article.
Target analysis of the experimental measles therapeutic AS-136A.
Yoon JJ, Krumm SA, Ndungu JM, Hoffman V, Bankamp B, Rota PA, Sun A, Snyder JP, Plemper RK. Yoon JJ, et al. Among authors: plemper rk. Antimicrob Agents Chemother. 2009 Sep;53(9):3860-70. doi: 10.1128/AAC.00503-09. Epub 2009 Jun 15. Antimicrob Agents Chemother. 2009. PMID: 19528268 Free PMC article.
140 results