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Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety.
Cohen F, Aggen JB, Andrews LD, Assar Z, Boggs J, Choi T, Dozzo P, Easterday AN, Haglund CM, Hildebrandt DJ, Holt MC, Joly K, Jubb A, Kamal Z, Kane TR, Konradi AW, Krause KM, Linsell MS, Machajewski TD, Miroshnikova O, Moser HE, Nieto V, Phan T, Plato C, Serio AW, Seroogy J, Shakhmin A, Stein AJ, Sun AD, Sviridov S, Wang Z, Wlasichuk K, Yang W, Zhou X, Zhu H, Cirz RT. Cohen F, et al. Among authors: plato c. ChemMedChem. 2019 Aug 20;14(16):1560-1572. doi: 10.1002/cmdc.201900287. Epub 2019 Aug 5. ChemMedChem. 2019. PMID: 31283109
Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis.
Lefebvre E, Moyle G, Reshef R, Richman LP, Thompson M, Hong F, Chou HL, Hashiguchi T, Plato C, Poulin D, Richards T, Yoneyama H, Jenkins H, Wolfgang G, Friedman SL. Lefebvre E, et al. Among authors: plato c. PLoS One. 2016 Jun 27;11(6):e0158156. doi: 10.1371/journal.pone.0158156. eCollection 2016. PLoS One. 2016. PMID: 27347680 Free PMC article.
Design and Synthesis of Piperazine-Based Compounds Conjugated to Humanized Ferritin as Delivery System of siRNA in Cancer Cells.
Pediconi N, Ghirga F, Del Plato C, Peruzzi G, Athanassopoulos CM, Mori M, Crestoni ME, Corinti D, Ugozzoli F, Massera C, Arcovito A, Botta B, Boffi A, Quaglio D, Baiocco P. Pediconi N, et al. Among authors: del plato c. Bioconjug Chem. 2021 Jun 16;32(6):1105-1116. doi: 10.1021/acs.bioconjchem.1c00137. Epub 2021 May 12. Bioconjug Chem. 2021. PMID: 33978420 Free PMC article.
The Revaluation of Plant-Derived Terpenes to Fight Antibiotic-Resistant Infections.
Cappiello F, Loffredo MR, Del Plato C, Cammarone S, Casciaro B, Quaglio D, Mangoni ML, Botta B, Ghirga F. Cappiello F, et al. Among authors: del plato c. Antibiotics (Basel). 2020 Jun 13;9(6):325. doi: 10.3390/antibiotics9060325. Antibiotics (Basel). 2020. PMID: 32545761 Free PMC article. Review.
Site-Directed Antibody Immobilization by Resorc[4]arene-Based Immunosensors.
Quaglio D, Mangiardi L, Venditti G, Del Plato C, Polli F, Ghirga F, Favero G, Pierini M, Botta B, Mazzei F. Quaglio D, et al. Among authors: del plato c. Chemistry. 2020 Jul 8;26(38):8400-8406. doi: 10.1002/chem.202000989. Epub 2020 Jun 25. Chemistry. 2020. PMID: 32240571
Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans.
Spencer AG, Labonte ED, Rosenbaum DP, Plato CF, Carreras CW, Leadbetter MR, Kozuka K, Kohler J, Koo-McCoy S, He L, Bell N, Tabora J, Joly KM, Navre M, Jacobs JW, Charmot D. Spencer AG, et al. Among authors: plato cf. Sci Transl Med. 2014 Mar 12;6(227):227ra36. doi: 10.1126/scitranslmed.3007790. Sci Transl Med. 2014. PMID: 24622516 Clinical Trial.
131 results