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Tools for computational design and high-throughput screening of therapeutic enzymes.
Vasina M, Velecký J, Planas-Iglesias J, Marques SM, Skarupova J, Damborsky J, Bednar D, Mazurenko S, Prokop Z. Vasina M, et al. Among authors: planas iglesias j. Adv Drug Deliv Rev. 2022 Apr;183:114143. doi: 10.1016/j.addr.2022.114143. Epub 2022 Feb 12. Adv Drug Deliv Rev. 2022. PMID: 35167900 Review.
Computational design of enzymes for biotechnological applications.
Planas-Iglesias J, Marques SM, Pinto GP, Musil M, Stourac J, Damborsky J, Bednar D. Planas-Iglesias J, et al. Biotechnol Adv. 2021 Mar-Apr;47:107696. doi: 10.1016/j.biotechadv.2021.107696. Epub 2021 Jan 26. Biotechnol Adv. 2021. PMID: 33513434 Review.
Web-based tools for computational enzyme design.
Marques SM, Planas-Iglesias J, Damborsky J. Marques SM, et al. Among authors: planas iglesias j. Curr Opin Struct Biol. 2021 Aug;69:19-34. doi: 10.1016/j.sbi.2021.01.010. Epub 2021 Mar 2. Curr Opin Struct Biol. 2021. PMID: 33667757 Review.
Engineering the protein dynamics of an ancestral luciferase.
Schenkmayerova A, Pinto GP, Toul M, Marek M, Hernychova L, Planas-Iglesias J, Daniel Liskova V, Pluskal D, Vasina M, Emond S, Dörr M, Chaloupkova R, Bednar D, Prokop Z, Hollfelder F, Bornscheuer UT, Damborsky J. Schenkmayerova A, et al. Among authors: planas iglesias j. Nat Commun. 2021 Jun 14;12(1):3616. doi: 10.1038/s41467-021-23450-z. Nat Commun. 2021. PMID: 34127663 Free PMC article.
LoopGrafter: Visual Support for the Grafting Workflow of Protein Loops.
Opaleny F, Ulbrich P, Planas-Iglesias J, Byska J, Pinto GP, Bednar D, FurmanovA K, KozlikovA B. Opaleny F, et al. Among authors: planas iglesias j. IEEE Trans Vis Comput Graph. 2021 Sep 29;PP. doi: 10.1109/TVCG.2021.3114755. Online ahead of print. IEEE Trans Vis Comput Graph. 2021. PMID: 34587016
Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.
Sieberts SK, Zhu F, García-García J, Stahl E, Pratap A, Pandey G, Pappas D, Aguilar D, Anton B, Bonet J, Eksi R, Fornés O, Guney E, Li H, Marín MA, Panwar B, Planas-Iglesias J, Poglayen D, Cui J, Falcao AO, Suver C, Hoff B, Balagurusamy VSK, Dillenberger D, Neto EC, Norman T, Aittokallio T, Ammad-Ud-Din M, Azencott CA, Bellón V, Boeva V, Bunte K, Chheda H, Cheng L, Corander J, Dumontier M, Goldenberg A, Gopalacharyulu P, Hajiloo M, Hidru D, Jaiswal A, Kaski S, Khalfaoui B, Khan SA, Kramer ER, Marttinen P, Mezlini AM, Molparia B, Pirinen M, Saarela J, Samwald M, Stoven V, Tang H, Tang J, Torkamani A, Vert JP, Wang B, Wang T, Wennerberg K, Wineinger NE, Xiao G, Xie Y, Yeung R, Zhan X, Zhao C; Members of the Rheumatoid Arthritis Challenge Consortium; Greenberg J, Kremer J, Michaud K, Barton A, Coenen M, Mariette X, Miceli C, Shadick N, Weinblatt M, de Vries N, Tak PP, Gerlag D, Huizinga TWJ, Kurreeman F, Allaart CF, Louis Bridges S Jr, Criswell L, Moreland L, Klareskog L, Saevarsdottir S, Padyukov L, Gregersen PK, Friend S, Plenge R, Stolovitzky G, Oliva B, Guan Y, Mangravite LM. Sieberts SK, et al. Nat Commun. 2016 Aug 23;7:12460. doi: 10.1038/ncomms12460. Nat Commun. 2016. PMID: 27549343 Free PMC article.
36 results