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Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia.
Laurila PP, Wohlwend M, Imamura de Lima T, Luan P, Herzig S, Zanou N, Crisol B, Bou-Sleiman M, Porcu E, Gallart-Ayala H, Handzlik MK, Wang Q, Jain S, D'Amico D, Salonen M, Metallo CM, Kutalik Z, Eichmann TO, Place N, Ivanisevic J, Lahti J, Eriksson JG, Auwerx J. Laurila PP, et al. Among authors: place n. Nat Aging. 2022 Dec;2(12):1159-1175. doi: 10.1038/s43587-022-00309-6. Epub 2022 Dec 16. Nat Aging. 2022. PMID: 37118545
Three weeks of sprint interval training improved high-intensity cycling performance and limited ryanodine receptor modifications in recreationally active human subjects.
Schlittler M, Neyroud D, Tanga C, Zanou N, Kamandulis S, Skurvydas A, Kayser B, Westerblad H, Place N, Andersson DC. Schlittler M, et al. Among authors: place n. Eur J Appl Physiol. 2019 Sep;119(9):1951-1958. doi: 10.1007/s00421-019-04183-w. Epub 2019 Jun 27. Eur J Appl Physiol. 2019. PMID: 31250088
Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity.
Zanou N, Dridi H, Reiken S, Imamura de Lima T, Donnelly C, De Marchi U, Ferrini M, Vidal J, Sittenfeld L, Feige JN, Garcia-Roves PM, Lopez-Mejia IC, Marks AR, Auwerx J, Kayser B, Place N. Zanou N, et al. Among authors: place n. Nat Commun. 2021 Dec 10;12(1):7219. doi: 10.1038/s41467-021-27422-1. Nat Commun. 2021. PMID: 34893614 Free PMC article.
Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy.
Laurila PP, Luan P, Wohlwend M, Zanou N, Crisol B, Imamura de Lima T, Goeminne LJE, Gallart-Ayala H, Shong M, Ivanisevic J, Place N, Auwerx J. Laurila PP, et al. Among authors: place n. Sci Adv. 2022 Jan 28;8(4):eabh4423. doi: 10.1126/sciadv.abh4423. Epub 2022 Jan 28. Sci Adv. 2022. PMID: 35089797 Free PMC article.
Toxic doses of caffeine are needed to increase skeletal muscle contractility.
Neyroud D, Cheng AJ, Donnelly C, Bourdillon N, Gassner AL, Geiser L, Rudaz S, Kayser B, Westerblad H, Place N. Neyroud D, et al. Among authors: place n. Am J Physiol Cell Physiol. 2019 Feb 1;316(2):C246-C251. doi: 10.1152/ajpcell.00269.2018. Epub 2018 Dec 19. Am J Physiol Cell Physiol. 2019. PMID: 30566390 Free article.
176 results