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mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder.
Gurgone A, Pizzo R, Raspanti A, Chiantia G, Devi S, Comai D, Morello N, Pilotto F, Gnavi S, Lupori L, Mazziotti R, Sagona G, Putignano E, Nocentini A, Supuran CT, Marcantoni A, Pizzorusso T, Giustetto M. Gurgone A, et al. Among authors: pizzo r. Neuropsychopharmacology. 2023 May;48(6):877-886. doi: 10.1038/s41386-022-01412-3. Epub 2022 Aug 9. Neuropsychopharmacology. 2023. PMID: 35945276 Free PMC article.
JNK signaling provides a novel therapeutic target for Rett syndrome.
Musi CA, Castaldo AM, Valsecchi AE, Cimini S, Morello N, Pizzo R, Renieri A, Meloni I, Bonati M, Giustetto M, Borsello T. Musi CA, et al. Among authors: pizzo r. BMC Biol. 2021 Dec 16;19(1):256. doi: 10.1186/s12915-021-01190-2. BMC Biol. 2021. PMID: 34911542 Free PMC article.
Age-Related Cognitive and Motor Decline in a Mouse Model of CDKL5 Deficiency Disorder is Associated with Increased Neuronal Senescence and Death.
Gennaccaro L, Fuchs C, Loi M, Pizzo R, Alvente S, Berteotti C, Lupori L, Sagona G, Galvani G, Gurgone A, Raspanti A, Medici G, Tassinari M, Trazzi S, Ren E, Rimondini R, Pizzorusso T, Zoccoli G, Giustetto M, Ciani E. Gennaccaro L, et al. Among authors: pizzo r. Aging Dis. 2021 Jun 1;12(3):764-785. doi: 10.14336/AD.2020.0827. eCollection 2021 Jun. Aging Dis. 2021. PMID: 34094641 Free PMC article.
48 results