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Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.
Papa A, Zakharov SI, Katchman AN, Kushner JS, Chen BX, Yang L, Liu G, Jimenez AS, Eisert RJ, Bradshaw GA, Dun W, Ali SR, Rodriques A, Zhou K, Topkara V, Yang M, Morrow JP, Tsai EJ, Karlin A, Wan E, Kalocsay M, Pitt GS, Colecraft HM, Ben-Johny M, Marx SO. Papa A, et al. Among authors: pitt gs. Nat Cardiovasc Res. 2022 Nov;1(11):1022-1038. doi: 10.1038/s44161-022-00157-y. Epub 2022 Nov 14. Nat Cardiovasc Res. 2022. PMID: 36424916 Free PMC article.
Remodeled cardiac calcium channels.
Pitt GS, Dun W, Boyden PA. Pitt GS, et al. J Mol Cell Cardiol. 2006 Sep;41(3):373-88. doi: 10.1016/j.yjmcc.2006.06.071. Epub 2006 Aug 8. J Mol Cell Cardiol. 2006. PMID: 16901502 Review.
Calmodulin limits pathogenic Na+ channel persistent current.
Yan H, Wang C, Marx SO, Pitt GS. Yan H, et al. Among authors: pitt gs. J Gen Physiol. 2017 Feb;149(2):277-293. doi: 10.1085/jgp.201611721. Epub 2017 Jan 13. J Gen Physiol. 2017. PMID: 28087622 Free PMC article.
Mechanism of adrenergic CaV1.2 stimulation revealed by proximity proteomics.
Liu G, Papa A, Katchman AN, Zakharov SI, Roybal D, Hennessey JA, Kushner J, Yang L, Chen BX, Kushnir A, Dangas K, Gygi SP, Pitt GS, Colecraft HM, Ben-Johny M, Kalocsay M, Marx SO. Liu G, et al. Among authors: pitt gs. Nature. 2020 Jan;577(7792):695-700. doi: 10.1038/s41586-020-1947-z. Epub 2020 Jan 22. Nature. 2020. PMID: 31969708 Free PMC article.
Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding-deficient channels.
Abrams J, Roybal D, Chakouri N, Katchman AN, Weinberg R, Yang L, Chen BX, Zakharov SI, Hennessey JA, Avula UMR, Diaz J, Wang C, Wan EY, Pitt GS, Ben-Johny M, Marx SO. Abrams J, et al. Among authors: pitt gs. JCI Insight. 2020 Oct 2;5(19):e141736. doi: 10.1172/jci.insight.141736. JCI Insight. 2020. PMID: 32870823 Free PMC article.
116 results