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A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.
Ghigo A, Murabito A, Sala V, Pisano AR, Bertolini S, Gianotti A, Caci E, Montresor A, Premchandar A, Pirozzi F, Ren K, Della Sala A, Mergiotti M, Richter W, de Poel E, Matthey M, Caldrer S, Cardone RA, Civiletti F, Costamagna A, Quinney NL, Butnarasu C, Visentin S, Ruggiero MR, Baroni S, Crich SG, Ramel D, Laffargue M, Tocchetti CG, Levi R, Conti M, Lu XY, Melotti P, Sorio C, De Rose V, Facchinetti F, Fanelli V, Wenzel D, Fleischmann BK, Mall MA, Beekman J, Laudanna C, Gentzsch M, Lukacs GL, Pedemonte N, Hirsch E. Ghigo A, et al. Among authors: pirozzi f. Sci Transl Med. 2022 Mar 30;14(638):eabl6328. doi: 10.1126/scitranslmed.abl6328. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353541 Free PMC article.
Mechanisms underlying the cross-talk between heart and cancer.
Brancaccio M, Pirozzi F, Hirsch E, Ghigo A. Brancaccio M, et al. Among authors: pirozzi f. J Physiol. 2020 Jul;598(14):3015-3027. doi: 10.1113/JP276746. Epub 2019 Jul 26. J Physiol. 2020. PMID: 31278748 Free article. Review.
Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth.
Li M, Sala V, De Santis MC, Cimino J, Cappello P, Pianca N, Di Bona A, Margaria JP, Martini M, Lazzarini E, Pirozzi F, Rossi L, Franco I, Bornbaum J, Heger J, Rohrbach S, Perino A, Tocchetti CG, Lima BHF, Teixeira MM, Porporato PE, Schulz R, Angelini A, Sandri M, Ameri P, Sciarretta S, Lima-Júnior RCP, Mongillo M, Zaglia T, Morello F, Novelli F, Hirsch E, Ghigo A. Li M, et al. Among authors: pirozzi f. Circulation. 2018 Aug 14;138(7):696-711. doi: 10.1161/CIRCULATIONAHA.117.030352. Circulation. 2018. PMID: 29348263 Free article.
Prevention of cancer therapy-related heart failure, is it really possible?
Cuomo A, Pirozzi F, Abete P, Tocchetti CG, Mercurio V. Cuomo A, et al. Among authors: pirozzi f. J Cardiovasc Med (Hagerstown). 2021 Jun 1;22(6):441-443. doi: 10.2459/JCM.0000000000001140. J Cardiovasc Med (Hagerstown). 2021. PMID: 33278210 No abstract available.
Oxidative stress in anticancer therapies-related cardiac dysfunction.
Attanasio U, Pirozzi F, Poto R, Cuomo A, Carannante A, Russo M, Ghigo A, Hirsch E, Tocchetti CG, Varricchi G, Mercurio V. Attanasio U, et al. Among authors: pirozzi f. Free Radic Biol Med. 2021 Jun;169:410-415. doi: 10.1016/j.freeradbiomed.2021.04.021. Epub 2021 Apr 28. Free Radic Biol Med. 2021. PMID: 33930514
Models of Heart Failure Based on the Cardiotoxicity of Anticancer Drugs.
Mercurio V, Pirozzi F, Lazzarini E, Marone G, Rizzo P, Agnetti G, Tocchetti CG, Ghigo A, Ameri P. Mercurio V, et al. Among authors: pirozzi f. J Card Fail. 2016 Jun;22(6):449-58. doi: 10.1016/j.cardfail.2016.04.008. Epub 2016 Apr 18. J Card Fail. 2016. PMID: 27103426 Review.
182 results