Pirkkanen J - Search Results

1

Protracted Exposure to a Sub-background Radiation Environment Negatively Impacts the Anhydrobiotic Recovery of Desiccated Yeast Sentinels.

Lapointe MR, Laframboise T, Pirkkanen J, Tai TC, Lees SJ, Santa Maria SR, Tharmalingam S, Boreham DR, Thome C. Lapointe MR, et al. Among authors: pirkkanen j. Health Phys. 2024 Jun 1;126(6):397-404. doi: 10.1097/HP.0000000000001804. Epub 2024 Apr 3. Health Phys. 2024. PMID: 38568172

2

Acute Impacts of Ionizing Radiation Exposure on the Gastrointestinal Tract and Gut Microbiome in Mice.

Jameus A, Dougherty J, Narendrula R, Levert D, Valiquette M, Pirkkanen J, Lalonde C, Bonin P, Gagnon JD, Appanna VD, Tharmalingam S, Thome C. Jameus A, et al. Among authors: pirkkanen j. Int J Mol Sci. 2024 Mar 15;25(6):3339. doi: 10.3390/ijms25063339. Int J Mol Sci. 2024. PMID: 38542312 Free PMC article.

3

Overexpression of FRA1 (FOSL1) Leads to Global Transcriptional Perturbations, Reduced Cellular Adhesion and Altered Cell Cycle Progression.

Al-Khayyat W, Pirkkanen J, Dougherty J, Laframboise T, Dickinson N, Khaper N, Lees SJ, Mendonca MS, Boreham DR, Tai TC, Thome C, Tharmalingam S. Al-Khayyat W, et al. Among authors: pirkkanen j. Cells. 2023 Sep 24;12(19):2344. doi: 10.3390/cells12192344. Cells. 2023. PMID: 37830558 Free PMC article.

4

Genomic Loss and Epigenetic Silencing of the FOSL1 Tumor Suppressor Gene in Radiation-induced Neoplastic Transformation of Human CGL1 Cells Alters the Tumorigenic Phenotype In Vitro and In Vivo.

Pirkkanen J, Tharmalingam S, Thome C, Sinex HC, Benjamin LV, Losch AC, Borgmann AJ, Dhaemers RM, Gordon C, Boreham DR, Mendonca MS. Pirkkanen J, et al. Radiat Res. 2023 Jul 1;200(1):48-64. doi: 10.1667/RADE-22-00216.1. Radiat Res. 2023. PMID: 37141110 Free PMC article.

5

The REPAIR Project, a Deep-Underground Radiobiology Experiment Investigating the Biological Effects of Natural Background Radiation: The First 6 Years.

Pirkkanen J, Lalonde C, Lapointe M, Laframboise T, Mendonca MS, Boreham DR, Tharmalingam S, Thome C. Pirkkanen J, et al. Radiat Res. 2023 Mar 1;199(3):290-293. doi: 10.1667/RADE-22-00193.1. Radiat Res. 2023. PMID: 36745561

6

Radiation-Induced Alterations in Proliferation, Migration, and Adhesion in Lens Epithelial Cells and Implications for Cataract Development.

Vigneux G, Pirkkanen J, Laframboise T, Prescott H, Tharmalingam S, Thome C. Vigneux G, et al. Among authors: pirkkanen j. Bioengineering (Basel). 2022 Jan 12;9(1):29. doi: 10.3390/bioengineering9010029. Bioengineering (Basel). 2022. PMID: 35049738 Free PMC article.

7

DOSIMETRIC CHARACTERISATION OF A SUB-NATURAL BACKGROUND RADIATION ENVIRONMENT FOR RADIOBIOLOGY INVESTIGATIONS.

Kennedy KJ, LeBlanc A, Pirkkanen J, Thome C, Tai TC, LeClair R, Boreham DR. Kennedy KJ, et al. Among authors: pirkkanen j. Radiat Prot Dosimetry. 2021 Sep 8;195(2):114-123. doi: 10.1093/rpd/ncab120. Radiat Prot Dosimetry. 2021. PMID: 34402520

8

A novel specialized tissue culture incubator designed and engineered for radiobiology experiments in a sub-natural background radiation research environment.

Pirkkanen J, Laframboise T, Liimatainen P, Sonley T, Stankiewicz S, Hood M, Obaid M, Zarnke A, Tai TC, Lees SJ, Boreham DR, Thome C. Pirkkanen J, et al. J Environ Radioact. 2021 Mar;228:106512. doi: 10.1016/j.jenvrad.2020.106512. Epub 2020 Dec 17. J Environ Radioact. 2021. PMID: 33341751

9

Transcriptomic profiling of gamma ray induced mutants from the CGL1 human hybrid cell system reveals novel insights into the mechanisms of radiation-induced carcinogenesis.

Pirkkanen J, Tharmalingam S, Morais IH, Lam-Sidun D, Thome C, Zarnke AM, Benjamin LV, Losch AC, Borgmann AJ, Sinex HC, Mendonca MS, Boreham DR. Pirkkanen J, et al. Free Radic Biol Med. 2019 Dec;145:300-311. doi: 10.1016/j.freeradbiomed.2019.09.037. Epub 2019 Sep 30. Free Radic Biol Med. 2019. PMID: 31580949

10

Physical and chemical characterization of McIntyre Powder: An aluminum dust inhaled by miners to combat silicosis.

Zarnke A, Rasmussen PE, David MO, Eidi H, Kennedy K, Hedges K, Irick T, Thome C, Pirkkanen J, Boreham D. Zarnke A, et al. Among authors: pirkkanen j. J Occup Environ Hyg. 2019 Nov;16(11):745-756. doi: 10.1080/15459624.2019.1657581. Epub 2019 Sep 18. J Occup Environ Hyg. 2019. PMID: 31532354

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