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An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates.
Goveia J, Rohlenova K, Taverna F, Treps L, Conradi LC, Pircher A, Geldhof V, de Rooij LPMH, Kalucka J, Sokol L, García-Caballero M, Zheng Y, Qian J, Teuwen LA, Khan S, Boeckx B, Wauters E, Decaluwé H, De Leyn P, Vansteenkiste J, Weynand B, Sagaert X, Verbeken E, Wolthuis A, Topal B, Everaerts W, Bohnenberger H, Emmert A, Panovska D, De Smet F, Staal FJT, Mclaughlin RJ, Impens F, Lagani V, Vinckier S, Mazzone M, Schoonjans L, Dewerchin M, Eelen G, Karakach TK, Yang H, Wang J, Bolund L, Lin L, Thienpont B, Li X, Lambrechts D, Luo Y, Carmeliet P. Goveia J, et al. Among authors: pircher a. Cancer Cell. 2020 Jan 13;37(1):21-36.e13. doi: 10.1016/j.ccell.2019.12.001. Cancer Cell. 2020. PMID: 31935371 Free article.
The liver-resident immune cell repertoire - A boon or a bane during machine perfusion?
Fodor M, Salcher S, Gottschling H, Mair A, Blumer M, Sopper S, Ebner S, Pircher A, Oberhuber R, Wolf D, Schneeberger S, Hautz T. Fodor M, et al. Among authors: pircher a. Front Immunol. 2022 Oct 13;13:982018. doi: 10.3389/fimmu.2022.982018. eCollection 2022. Front Immunol. 2022. PMID: 36311746 Free PMC article. Review.
Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver.
Hautz T, Salcher S, Fodor M, Sturm G, Ebner S, Mair A, Trebo M, Untergasser G, Sopper S, Cardini B, Martowicz A, Hofmann J, Daum S, Kalb M, Resch T, Krendl F, Weissenbacher A, Otarashvili G, Obrist P, Zelger B, Öfner D, Trajanoski Z, Troppmair J, Oberhuber R, Pircher A, Wolf D, Schneeberger S. Hautz T, et al. Among authors: pircher a. Nat Commun. 2023 Apr 21;14(1):2285. doi: 10.1038/s41467-023-37674-8. Nat Commun. 2023. PMID: 37085477 Free PMC article.
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.
Cantelmo AR, Conradi LC, Brajic A, Goveia J, Kalucka J, Pircher A, Chaturvedi P, Hol J, Thienpont B, Teuwen LA, Schoors S, Boeckx B, Vriens J, Kuchnio A, Veys K, Cruys B, Finotto L, Treps L, Stav-Noraas TE, Bifari F, Stapor P, Decimo I, Kampen K, De Bock K, Haraldsen G, Schoonjans L, Rabelink T, Eelen G, Ghesquière B, Rehman J, Lambrechts D, Malik AB, Dewerchin M, Carmeliet P. Cantelmo AR, et al. Among authors: pircher a. Cancer Cell. 2016 Dec 12;30(6):968-985. doi: 10.1016/j.ccell.2016.10.006. Epub 2016 Nov 17. Cancer Cell. 2016. PMID: 27866851 Free PMC article.
Vessel pruning or healing: endothelial metabolism as a novel target?
Cantelmo AR, Pircher A, Kalucka J, Carmeliet P. Cantelmo AR, et al. Among authors: pircher a. Expert Opin Ther Targets. 2017 Mar;21(3):239-247. doi: 10.1080/14728222.2017.1282465. Epub 2017 Jan 27. Expert Opin Ther Targets. 2017. PMID: 28081641 Free PMC article. Review.
Tumor vessel disintegration by maximum tolerable PFKFB3 blockade.
Conradi LC, Brajic A, Cantelmo AR, Bouché A, Kalucka J, Pircher A, Brüning U, Teuwen LA, Vinckier S, Ghesquière B, Dewerchin M, Carmeliet P. Conradi LC, et al. Among authors: pircher a. Angiogenesis. 2017 Nov;20(4):599-613. doi: 10.1007/s10456-017-9573-6. Epub 2017 Sep 5. Angiogenesis. 2017. PMID: 28875379
141 results