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A marine microbiome antifungal targets urgent-threat drug-resistant fungi.
Zhang F, Zhao M, Braun DR, Ericksen SS, Piotrowski JS, Nelson J, Peng J, Ananiev GE, Chanana S, Barns K, Fossen J, Sanchez H, Chevrette MG, Guzei IA, Zhao C, Guo L, Tang W, Currie CR, Rajski SR, Audhya A, Andes DR, Bugni TS. Zhang F, et al. Among authors: piotrowski js. Science. 2020 Nov 20;370(6519):974-978. doi: 10.1126/science.abd6919. Science. 2020. PMID: 33214279 Free PMC article.
Forazoline A: marine-derived polyketide with antifungal in vivo efficacy.
Wyche TP, Piotrowski JS, Hou Y, Braun D, Deshpande R, McIlwain S, Ong IM, Myers CL, Guzei IA, Westler WM, Andes DR, Bugni TS. Wyche TP, et al. Among authors: piotrowski js. Angew Chem Int Ed Engl. 2014 Oct 20;53(43):11583-6. doi: 10.1002/anie.201405990. Epub 2014 Sep 4. Angew Chem Int Ed Engl. 2014. PMID: 25197007 Free PMC article.
Coculture of Marine Invertebrate-Associated Bacteria and Interdisciplinary Technologies Enable Biosynthesis and Discovery of a New Antibiotic, Keyicin.
Adnani N, Chevrette MG, Adibhatla SN, Zhang F, Yu Q, Braun DR, Nelson J, Simpkins SW, McDonald BR, Myers CL, Piotrowski JS, Thompson CJ, Currie CR, Li L, Rajski SR, Bugni TS. Adnani N, et al. Among authors: piotrowski js. ACS Chem Biol. 2017 Dec 15;12(12):3093-3102. doi: 10.1021/acschembio.7b00688. Epub 2017 Nov 22. ACS Chem Biol. 2017. PMID: 29121465 Free PMC article.
Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin.
Wyche TP, Alvarenga RFR, Piotrowski JS, Duster MN, Warrack SR, Cornilescu G, De Wolfe TJ, Hou Y, Braun DR, Ellis GA, Simpkins SW, Nelson J, Myers CL, Steele J, Mori H, Safdar N, Markley JL, Rajski SR, Bugni TS. Wyche TP, et al. Among authors: piotrowski js. ACS Chem Biol. 2017 Sep 15;12(9):2287-2295. doi: 10.1021/acschembio.7b00388. Epub 2017 Jul 26. ACS Chem Biol. 2017. PMID: 28708379 Free PMC article.
A global genetic interaction network maps a wiring diagram of cellular function.
Costanzo M, VanderSluis B, Koch EN, Baryshnikova A, Pons C, Tan G, Wang W, Usaj M, Hanchard J, Lee SD, Pelechano V, Styles EB, Billmann M, van Leeuwen J, van Dyk N, Lin ZY, Kuzmin E, Nelson J, Piotrowski JS, Srikumar T, Bahr S, Chen Y, Deshpande R, Kurat CF, Li SC, Li Z, Usaj MM, Okada H, Pascoe N, San Luis BJ, Sharifpoor S, Shuteriqi E, Simpkins SW, Snider J, Suresh HG, Tan Y, Zhu H, Malod-Dognin N, Janjic V, Przulj N, Troyanskaya OG, Stagljar I, Xia T, Ohya Y, Gingras AC, Raught B, Boutros M, Steinmetz LM, Moore CL, Rosebrock AP, Caudy AA, Myers CL, Andrews B, Boone C. Costanzo M, et al. Among authors: piotrowski js. Science. 2016 Sep 23;353(6306):aaf1420. doi: 10.1126/science.aaf1420. Science. 2016. PMID: 27708008 Free PMC article.
Plant-derived antifungal agent poacic acid targets β-1,3-glucan.
Piotrowski JS, Okada H, Lu F, Li SC, Hinchman L, Ranjan A, Smith DL, Higbee AJ, Ulbrich A, Coon JJ, Deshpande R, Bukhman YV, McIlwain S, Ong IM, Myers CL, Boone C, Landick R, Ralph J, Kabbage M, Ohya Y. Piotrowski JS, et al. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1490-7. doi: 10.1073/pnas.1410400112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775513 Free PMC article.
46 results