Pinto-Fernandez A - Search Results

1

Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection.

Munnur D, Teo Q, Eggermont D, Lee HHY, Thery F, Ho J, van Leur SW, Ng WWS, Siu LYL, Beling A, Ploegh H, Pinto-Fernandez A, Damianou A, Kessler B, Impens F, Mok CKP, Sanyal S. Munnur D, et al. Nat Immunol. 2021 Nov;22(11):1416-1427. doi: 10.1038/s41590-021-01035-8. Epub 2021 Oct 18. Nat Immunol. 2021. PMID: 34663977

2

DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic Targets.

Pinto-Fernandez A, Kessler BM. Pinto-Fernandez A, et al. Front Genet. 2016 Jul 28;7:133. doi: 10.3389/fgene.2016.00133. eCollection 2016. Front Genet. 2016. PMID: 27516771 Free PMC article. Review.

3

Regulation of the endosomal SNX27-retromer by OTULIN.

Stangl A, Elliott PR, Pinto-Fernandez A, Bonham S, Harrison L, Schaub A, Kutzner K, Keusekotten K, Pfluger PT, El Oualid F, Kessler BM, Komander D, Krappmann D. Stangl A, et al. Nat Commun. 2019 Sep 20;10(1):4320. doi: 10.1038/s41467-019-12309-z. Nat Commun. 2019. PMID: 31541095 Free PMC article.

4

Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics.

Pinto-Fernández A, Davis S, Schofield AB, Scott HC, Zhang P, Salah E, Mathea S, Charles PD, Damianou A, Bond G, Fischer R, Kessler BM. Pinto-Fernández A, et al. Front Chem. 2019 Aug 29;7:592. doi: 10.3389/fchem.2019.00592. eCollection 2019. Front Chem. 2019. PMID: 31555637 Free PMC article.

5

Ubiquitomics: An Overview and Future.

Vere G, Kealy R, Kessler BM, Pinto-Fernandez A. Vere G, et al. Biomolecules. 2020 Oct 17;10(10):1453. doi: 10.3390/biom10101453. Biomolecules. 2020. PMID: 33080838 Free PMC article. Review.

6

Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity.

Pinto-Fernandez A, Salio M, Partridge T, Chen J, Vere G, Greenwood H, Olie CS, Damianou A, Scott HC, Pegg HJ, Chiarenza A, Díaz-Saez L, Smith P, Gonzalez-Lopez C, Patel B, Anderton E, Jones N, Hammonds TR, Huber K, Muschel R, Borrow P, Cerundolo V, Kessler BM. Pinto-Fernandez A, et al. Br J Cancer. 2021 Feb;124(4):817-830. doi: 10.1038/s41416-020-01167-y. Epub 2020 Nov 20. Br J Cancer. 2021. PMID: 33214684 Free PMC article.

7

ABPP-HT - High-Throughput Activity-Based Profiling of Deubiquitylating Enzyme Inhibitors in a Cellular Context.

Jones HBL, Heilig R, Fischer R, Kessler BM, Pinto-Fernández A. Jones HBL, et al. Front Chem. 2021 Feb 25;9:640105. doi: 10.3389/fchem.2021.640105. eCollection 2021. Front Chem. 2021. PMID: 33718328 Free PMC article.

8

Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19.

Vere G, Alam MR, Farrar S, Kealy R, Kessler BM, O'Brien DP, Pinto-Fernández A. Vere G, et al. Biomolecules. 2022 Feb 12;12(2):300. doi: 10.3390/biom12020300. Biomolecules. 2022. PMID: 35204803 Free PMC article. Review.

9

ABPP-HT*-Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods.

Jones HBL, Heilig R, Davis S, Fischer R, Kessler BM, Pinto-Fernández A. Jones HBL, et al. Int J Mol Sci. 2022 Mar 17;23(6):3263. doi: 10.3390/ijms23063263. Int J Mol Sci. 2022. PMID: 35328685 Free PMC article.

10

The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.

Kaokhum N, Pinto-Fernández A, Wilkinson M, Kessler BM, Ismail HM. Kaokhum N, et al. Mol Cell Proteomics. 2022 Dec;21(12):100419. doi: 10.1016/j.mcpro.2022.100419. Epub 2022 Sep 28. Mol Cell Proteomics. 2022. PMID: 36182100 Free PMC article.

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