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Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.
Thomas MG, McGonagle K, Rowland P, Robinson DA, Dodd PG, Camino-Díaz I, Campbell L, Cantizani J, Castañeda P, Conn D, Craggs PD, Edwards D, Ferguson L, Fosberry A, Frame L, Goswami P, Hu X, Korczynska J, MacLean L, Martin J, Mutter N, Osuna-Cabello M, Paterson C, Peña I, Pinto EG, Pont C, Riley J, Shishikura Y, Simeons FRC, Stojanovski L, Thomas J, Wrobel K, Young RJ, Zmuda F, Zuccotto F, Read KD, Gilbert IH, Marco M, Miles TJ, Manzano P, De Rycker M. Thomas MG, et al. Among authors: pinto eg. J Med Chem. 2023 Aug 10;66(15):10413-10431. doi: 10.1021/acs.jmedchem.3c00582. Epub 2023 Jul 28. J Med Chem. 2023. PMID: 37506194 Free PMC article.
Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism.
MacLeod AK, Coquelin KS, Huertas L, Simeons FRC, Riley J, Casado P, Guijarro L, Casanueva R, Frame L, Pinto EG, Ferguson L, Duncan C, Mutter N, Shishikura Y, Henderson CJ, Cebrian D, Wolf CR, Read KD. MacLeod AK, et al. Among authors: pinto eg. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2315069121. doi: 10.1073/pnas.2315069121. Epub 2024 Feb 5. Proc Natl Acad Sci U S A. 2024. PMID: 38315851 Free PMC article.
Prediabetes remission after bariatric surgery: a 4-years follow-up study.
Borges-Canha M, Neves JS, Silva MM, Mendonça F, Moreno T, Ribeiro S, Vale C, Gonçalves J, Ferreira HU, Gil-Santos S, Calheiros R, Meira I, Menino J, Guerreiro V, Pedro J, Sande A, Souto SB, da Costa EL, Carvalho D, Freitas P; CRIO group. Borges-Canha M, et al. BMC Endocr Disord. 2024 Jan 11;24(1):7. doi: 10.1186/s12902-024-01537-0. BMC Endocr Disord. 2024. PMID: 38200480 Free PMC article.
Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.
McGonagle K, Tarver GJ, Cantizani J, Cotillo I, Dodd PG, Ferguson L, Gilbert IH, Marco M, Miles T, Naylor C, Osuna-Cabello M, Paterson C, Read KD, Pinto EG, Riley J, Scullion P, Shishikura Y, Simeons F, Stojanovski L, Svensen N, Thomas J, Wyatt PG, Manzano P, De Rycker M, Thomas MG. McGonagle K, et al. Among authors: pinto eg. Eur J Med Chem. 2022 Aug 5;238:114421. doi: 10.1016/j.ejmech.2022.114421. Epub 2022 May 6. Eur J Med Chem. 2022. PMID: 35594652 Free article.
CO-RADS: Coronavirus Classification Review.
Penha D, Pinto EG, Matos F, Hochhegger B, Monaghan C, Taborda-Barata L, Irion K, Marchiori E. Penha D, et al. Among authors: pinto eg. J Clin Imaging Sci. 2021 Feb 15;11:9. doi: 10.25259/JCIS_192_2020. eCollection 2021. J Clin Imaging Sci. 2021. PMID: 33767901 Free PMC article. Review.
Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses.
Alves Conserva GA, Quirós-Guerrero LM, Costa-Silva TA, Marcourt L, Pinto EG, Tempone AG, Fernandes JPS, Wolfender JL, Queiroz EF, Lago JHG. Alves Conserva GA, et al. Among authors: pinto eg. PLoS One. 2021 Feb 25;16(2):e0247334. doi: 10.1371/journal.pone.0247334. eCollection 2021. PLoS One. 2021. PMID: 33630860 Free PMC article.
37 results