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mTORC1 is a mechanosensor that regulates surfactant function and lung compliance during ventilator-induced lung injury.
Lee H, Fei Q, Streicher A, Zhang W, Isabelle C, Patel P, Lam HC, Arciniegas-Rubio A, Pinilla-Vera M, Amador-Munoz DP, Barragan-Bradford D, Higuera-Moreno A, Putman RK, Sholl LM, Henske EP, Bobba CM, Higuita-Castro N, Shalosky EM, Hite RD, Christman JW, Ghadiali SN, Baron RM, Englert JA. Lee H, et al. JCI Insight. 2021 Jul 22;6(14):e137708. doi: 10.1172/jci.insight.137708. JCI Insight. 2021. PMID: 34138757 Free PMC article.
Zinc deficiency primes the lung for ventilator-induced injury.
Boudreault F, Pinilla-Vera M, Englert JA, Kho AT, Isabelle C, Arciniegas AJ, Barragan-Bradford D, Quintana C, Amador-Munoz D, Guan J, Choi KM; MICU Registry; Sholl L, Hurwitz S, Tschumperlin DJ, Baron RM. Boudreault F, et al. JCI Insight. 2017 Jun 2;2(11):e86507. doi: 10.1172/jci.insight.86507. eCollection 2017 Jun 2. JCI Insight. 2017. PMID: 28570269 Free PMC article.
Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut.
Varon J, Arciniegas Rubio A, Amador-Munoz D, Corcoran A, DeCorte JA, Isabelle C, Pinilla Vera M, Walker K, Brown L, Cernadas M, Bry L, Yang H, Kitsios GD, McVerry BJ, Morris A, Lee H, Howrylak J, Englert JA, Baron RM. Varon J, et al. Among authors: pinilla vera m. Crit Care Explor. 2022 May 18;4(5):e0699. doi: 10.1097/CCE.0000000000000699. eCollection 2022 May. Crit Care Explor. 2022. PMID: 35620769 Free PMC article.
Single-cell transcriptomics reveal a hyperacute cytokine and immune checkpoint axis after cardiac arrest in patients with poor neurological outcome.
Tamura T, Cheng C, Chen W, Merriam LT, Athar H, Kim YH, Manandhar R, Amir Sheikh MD, Pinilla-Vera M, Varon J, Hou PC, Lawler PR, Oldham WM, Seethala RR, Tesfaigzi Y; Immunology of Cardiac Arrest Network (I-CAN); Weissman AJ, Baron RM, Ichinose F, Berg KM, Bohula EA, Morrow DA, Chen X, Kim EY. Tamura T, et al. Among authors: pinilla vera m. Med. 2023 Jul 14;4(7):432-456.e6. doi: 10.1016/j.medj.2023.05.003. Epub 2023 May 30. Med. 2023. PMID: 37257452
24 results