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A Plant Proteinase Inhibitor from Enterolobium contortisiliquum Attenuates Pulmonary Mechanics, Inflammation and Remodeling Induced by Elastase in Mice.
Theodoro-Júnior OA, Righetti RF, Almeida-Reis R, Martins-Oliveira BT, Oliva LV, Prado CM, Saraiva-Romanholo BM, Leick EA, Pinheiro NM, Lobo YA, Martins MA, Oliva ML, Tibério IF. Theodoro-Júnior OA, et al. Among authors: pinheiro nm. Int J Mol Sci. 2017 Feb 14;18(2):403. doi: 10.3390/ijms18020403. Int J Mol Sci. 2017. PMID: 28216579 Free PMC article.
Modulation of the oscillatory mechanics of lung tissue and the oxidative stress response induced by arginase inhibition in a chronic allergic inflammation model.
Aristoteles LR, Righetti RF, Pinheiro NM, Franco RB, Starling CM, da Silva JC, Pigati PA, Caperuto LC, Prado CM, Dolhnikoff M, Martins MA, Leick EA, Tibério IF. Aristoteles LR, et al. Among authors: pinheiro nm. BMC Pulm Med. 2013 Aug 15;13:52. doi: 10.1186/1471-2466-13-52. BMC Pulm Med. 2013. PMID: 23947680 Free PMC article.
Sakuranetin reverses vascular peribronchial and lung parenchyma remodeling in a murine model of chronic allergic pulmonary inflammation.
Sakoda CPP, de Toledo AC, Perini A, Pinheiro NM, Hiyane MI, Grecco SDS, de Fátima Lopes Calvo Tibério I, Câmara NOS, de Arruda Martins M, Lago JHG, Righetti RF, Prado CM. Sakoda CPP, et al. Among authors: pinheiro nm. Acta Histochem. 2016 Jul;118(6):615-624. doi: 10.1016/j.acthis.2016.07.001. Epub 2016 Jul 15. Acta Histochem. 2016. PMID: 27425653
Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema.
Games E, Guerreiro M, Santana FR, Pinheiro NM, de Oliveira EA, Lopes FD, Olivo CR, Tibério IF, Martins MA, Lago JH, Prado CM. Games E, et al. Among authors: pinheiro nm. Molecules. 2016 Oct 20;21(10):1390. doi: 10.3390/molecules21101390. Molecules. 2016. PMID: 27775634 Free PMC article.
Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS-induced acute lung injury.
Bittencourt-Mernak MI, Pinheiro NM, Santana FP, Guerreiro MP, Saraiva-Romanholo BM, Grecco SS, Caperuto LC, Felizardo RJ, Câmara NO, Tibério IF, Martins MA, Lago JH, Prado CM. Bittencourt-Mernak MI, et al. Among authors: pinheiro nm. Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L217-L230. doi: 10.1152/ajplung.00444.2015. Epub 2016 Nov 23. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 27881407 Free article.
A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases.
Taguchi L, Pinheiro NM, Olivo CR, Choqueta-Toledo A, Grecco SS, Lopes FD, Caperuto LC, Martins MA, Tiberio IF, Câmara NO, Lago JH, Prado CM. Taguchi L, et al. Among authors: pinheiro nm. Respir Res. 2015 Jun 30;16(1):79. doi: 10.1186/s12931-015-0233-3. Respir Res. 2015. PMID: 26122092 Free PMC article.
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