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MIRRAGGE - Minimum Information Required for Reproducible AGGregation Experiments.
Martins PM, Navarro S, Silva A, Pinto MF, Sárkány Z, Figueiredo F, Pereira PJB, Pinheiro F, Bednarikova Z, Burdukiewicz M, Galzitskaya OV, Gazova Z, Gomes CM, Pastore A, Serpell LC, Skrabana R, Smirnovas V, Ziaunys M, Otzen DE, Ventura S, Macedo-Ribeiro S. Martins PM, et al. Among authors: pinheiro f. Front Mol Neurosci. 2020 Nov 27;13:582488. doi: 10.3389/fnmol.2020.582488. eCollection 2020. Front Mol Neurosci. 2020. PMID: 33328883 Free PMC article. Review.
Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity.
Sant'Anna R, Gallego P, Robinson LZ, Pereira-Henriques A, Ferreira N, Pinheiro F, Esperante S, Pallares I, Huertas O, Almeida MR, Reixach N, Insa R, Velazquez-Campoy A, Reverter D, Reig N, Ventura S. Sant'Anna R, et al. Among authors: pinheiro f. Nat Commun. 2016 Feb 23;7:10787. doi: 10.1038/ncomms10787. Nat Commun. 2016. PMID: 26902880 Free PMC article.
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Pujols J, Peña-Díaz S, Lázaro DF, Peccati F, Pinheiro F, González D, Carija A, Navarro S, Conde-Giménez M, García J, Guardiola S, Giralt E, Salvatella X, Sancho J, Sodupe M, Outeiro TF, Dalfó E, Ventura S. Pujols J, et al. Among authors: pinheiro f. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486. doi: 10.1073/pnas.1804198115. Epub 2018 Sep 24. Proc Natl Acad Sci U S A. 2018. PMID: 30249646 Free PMC article.
Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm.
Peña-Díaz S, Pujols J, Pinheiro F, Santos J, Pallarés I, Navarro S, Conde-Gimenez M, García J, Salvatella X, Dalfó E, Sancho J, Ventura S. Peña-Díaz S, et al. Among authors: pinheiro f. Front Bioeng Biotechnol. 2020 Oct 16;8:588947. doi: 10.3389/fbioe.2020.588947. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 33178678 Free PMC article.
428 results