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Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.
Lee H, Fenster RJ, Pineda SS, Gibbs WS, Mohammadi S, Davila-Velderrain J, Garcia FJ, Therrien M, Novis HS, Gao F, Wilkinson H, Vogt T, Kellis M, LaVoie MJ, Heiman M. Lee H, et al. Among authors: pineda ss. Neuron. 2020 Sep 9;107(5):891-908.e8. doi: 10.1016/j.neuron.2020.06.021. Epub 2020 Jul 17. Neuron. 2020. PMID: 32681824 Free PMC article.
Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity.
Wertz MH, Mitchem MR, Pineda SS, Hachigian LJ, Lee H, Lau V, Powers A, Kulicke R, Madan GK, Colic M, Therrien M, Vernon A, Beja-Glasser VF, Hegde M, Gao F, Kellis M, Hart T, Doench JG, Heiman M. Wertz MH, et al. Among authors: pineda ss. Neuron. 2020 Apr 8;106(1):76-89.e8. doi: 10.1016/j.neuron.2020.01.004. Epub 2020 Jan 30. Neuron. 2020. PMID: 32004439 Free PMC article.
Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD.
Pineda SS, Lee H, Ulloa-Navas MJ, Linville RM, Garcia FJ, Galani K, Engelberg-Cook E, Castanedes MC, Fitzwalter BE, Pregent LJ, Gardashli ME, DeTure M, Vera-Garcia DV, Hucke ATS, Oskarsson BE, Murray ME, Dickson DW, Heiman M, Belzil VV, Kellis M. Pineda SS, et al. Cell. 2024 Apr 11;187(8):1971-1989.e16. doi: 10.1016/j.cell.2024.02.031. Epub 2024 Mar 22. Cell. 2024. PMID: 38521060
Dysregulation of the EphrinB2-EphB4 ratio in pediatric cerebral arteriovenous malformations is associated with endothelial cell dysfunction in vitro and functions as a novel noninvasive biomarker in patients.
Fehnel KP, Penn DL, Duggins-Warf M, Gruber M, Pineda S, Sesen J, Moses-Gardner A, Shah N, Driscoll J, Zurakowski D, Orbach DB, Smith ER. Fehnel KP, et al. Exp Mol Med. 2020 Apr;52(4):658-671. doi: 10.1038/s12276-020-0414-0. Epub 2020 Apr 14. Exp Mol Med. 2020. PMID: 32286515 Free PMC article.
Disease specific urinary biomarkers in the central nervous system.
Duggins-Warf M, Ghalali A, Sesen J, Martinez T, Fehnel KP, Pineda S, Zurakowski D, Smith ER. Duggins-Warf M, et al. Sci Rep. 2023 Nov 7;13(1):19244. doi: 10.1038/s41598-023-46763-z. Sci Rep. 2023. PMID: 37935834 Free PMC article.
The Deadly Toxin Arsenal of the Tree-Dwelling Australian Funnel-Web Spiders.
Cardoso FC, Pineda SS, Herzig V, Sunagar K, Shaikh NY, Jin AH, King GF, Alewood PF, Lewis RJ, Dutertre S. Cardoso FC, et al. Among authors: pineda ss. Int J Mol Sci. 2022 Oct 28;23(21):13077. doi: 10.3390/ijms232113077. Int J Mol Sci. 2022. PMID: 36361863 Free PMC article.
30 results