Pigoni M - Search Results

1

BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.

Causevic M, Dominko K, Malnar M, Vidatic L, Cermak S, Pigoni M, Kuhn PH, Colombo A, Havas D, Flunkert S, McDonald J, Gunnersen JM, Hutter-Paier B, Tahirovic S, Windisch M, Krainc D, Lichtenthaler SF, Hecimovic S. Causevic M, et al. Among authors: pigoni m. PLoS One. 2018 Jul 6;13(7):e0200344. doi: 10.1371/journal.pone.0200344. eCollection 2018. PLoS One. 2018. PMID: 29979789 Free PMC article.

2

Functions of the Alzheimer's Disease Protease BACE1 at the Synapse in the Central Nervous System.

Munro KM, Nash A, Pigoni M, Lichtenthaler SF, Gunnersen JM. Munro KM, et al. Among authors: pigoni m. J Mol Neurosci. 2016 Nov;60(3):305-315. doi: 10.1007/s12031-016-0800-1. Epub 2016 Jul 25. J Mol Neurosci. 2016. PMID: 27456313 Free PMC article. Review.

3

Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.

Pigoni M, Wanngren J, Kuhn PH, Munro KM, Gunnersen JM, Takeshima H, Feederle R, Voytyuk I, De Strooper B, Levasseur MD, Hrupka BJ, Müller SA, Lichtenthaler SF. Pigoni M, et al. Mol Neurodegener. 2016 Oct 5;11(1):67. doi: 10.1186/s13024-016-0134-z. Mol Neurodegener. 2016. PMID: 27716410 Free PMC article.

4

Seizure-6 proteins highlight BACE1 functions in neurobiology.

Pigoni M, Gunnersen JM, Lichtenthaler SF. Pigoni M, et al. Oncotarget. 2017 Jan 31;8(5):7214-7215. doi: 10.18632/oncotarget.13801. Oncotarget. 2017. PMID: 28055952 Free PMC article. No abstract available.

5

Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease.

Peters F, Salihoglu H, Pratsch K, Herzog E, Pigoni M, Sgobio C, Lichtenthaler SF, Neumann U, Herms J. Peters F, et al. Among authors: pigoni m. EMBO J. 2019 Dec 2;38(23):e102345. doi: 10.15252/embj.2019102345. Epub 2019 Nov 7. EMBO J. 2019. PMID: 31701556 Free PMC article.

6

Lack of Sez6 Family Proteins Impairs Motor Functions, Short-Term Memory, and Cognitive Flexibility and Alters Dendritic Spine Properties.

Nash A, Aumann TD, Pigoni M, Lichtenthaler SF, Takeshima H, Munro KM, Gunnersen JM. Nash A, et al. Among authors: pigoni m. Cereb Cortex. 2020 Apr 14;30(4):2167-2184. doi: 10.1093/cercor/bhz230. Cereb Cortex. 2020. PMID: 31711114

7

Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.

Pigoni M, Hsia HE, Hartmann J, Rudan Njavro J, Shmueli MD, Müller SA, Güner G, Tüshaus J, Kuhn PH, Kumar R, Gao P, Tran ML, Ramazanov B, Blank B, Hipgrave Ederveen AL, Von Blume J, Mulle C, Gunnersen JM, Wuhrer M, Rammes G, Busche MA, Koeglsperger T, Lichtenthaler SF. Pigoni M, et al. EMBO J. 2020 Aug 3;39(15):e103457. doi: 10.15252/embj.2019103457. Epub 2020 Jun 22. EMBO J. 2020. PMID: 32567721 Free PMC article.

8

The β-Secretase Substrate Seizure 6-Like Protein (SEZ6L) Controls Motor Functions in Mice.

Ong-Pålsson E, Njavro JR, Wilson Y, Pigoni M, Schmidt A, Müller SA, Meyer M, Hartmann J, Busche MA, Gunnersen JM, Munro KM, Lichtenthaler SF. Ong-Pålsson E, et al. Among authors: pigoni m. Mol Neurobiol. 2022 Feb;59(2):1183-1198. doi: 10.1007/s12035-021-02660-y. Epub 2021 Dec 27. Mol Neurobiol. 2022. PMID: 34958451 Free PMC article.

9

The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation.

Brummer T, Pigoni M, Rossello A, Wang H, Noy PJ, Tomlinson MG, Blobel CP, Lichtenthaler SF. Brummer T, et al. Among authors: pigoni m. FASEB J. 2018 Jul;32(7):3560-3573. doi: 10.1096/fj.201700823RR. Epub 2018 Feb 7. FASEB J. 2018. PMID: 29430990 Free PMC article.

In summary, our study demonstrates that mADAM10 autoproteolysis must be blocked to allow for the proper detection of mADAM10, which is essential for the correct interpretation of biochemical and cellular studies of ADAM10.-Brummer, T., Pigoni, M., Rossello, A., Wang …

In summary, our study demonstrates that mADAM10 autoproteolysis must be blocked to allow for the proper detection of mADAM10, which is essen …

10

Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor.

Scilabra SD, Pigoni M, Pravatá V, Schätzl T, Müller SA, Troeberg L, Lichtenthaler SF. Scilabra SD, et al. Among authors: pigoni m. Sci Rep. 2018 Oct 2;8(1):14697. doi: 10.1038/s41598-018-32910-4. Sci Rep. 2018. PMID: 30279425 Free PMC article.

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