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Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response.
Giuli MV, Diluvio G, Giuliani E, Franciosa G, Di Magno L, Pignataro MG, Tottone L, Nicoletti C, Besharat ZM, Peruzzi G, Pelullo M, Palermo R, Canettieri G, Talora C, d'Amati G, Bellavia D, Screpanti I, Checquolo S. Giuli MV, et al. Among authors: pignataro mg. Oncogenesis. 2020 Oct 18;9(10):93. doi: 10.1038/s41389-020-00279-7. Oncogenesis. 2020. PMID: 33071287 Free PMC article.
NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.
Diluvio G, Del Gaudio F, Giuli MV, Franciosa G, Giuliani E, Palermo R, Besharat ZM, Pignataro MG, Vacca A, d'Amati G, Maroder M, Talora C, Capalbo C, Bellavia D, Checquolo S. Diluvio G, et al. Among authors: pignataro mg. Oncogenesis. 2018 May 25;7(5):42. doi: 10.1038/s41389-018-0051-9. Oncogenesis. 2018. PMID: 29795369 Free PMC article.
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects.
Perli E, Pisano A, Pignataro MG, Campese AF, Pelullo M, Genovese I, de Turris V, Ghelli AM, Cerbelli B, Giordano C, Colotti G, Morea V, d'Amati G. Perli E, et al. Among authors: pignataro mg. FASEB J. 2020 Jun;34(6):7675-7686. doi: 10.1096/fj.201903270R. Epub 2020 Apr 18. FASEB J. 2020. PMID: 32304340
Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology.
Valentini V, Silvestri V, Bucalo A, Conti G, Karimi M, Di Francesco L, Pomati G, Mezi S, Cerbelli B, Pignataro MG, Nicolussi A, Coppa A, D'Amati G, Giannini G, Ottini L. Valentini V, et al. Among authors: pignataro mg. Front Oncol. 2023 Jan 6;12:1092201. doi: 10.3389/fonc.2022.1092201. eCollection 2022. Front Oncol. 2023. PMID: 36686738 Free PMC article.
Novel compound mutations in the mitochondrial translation elongation factor (TSFM) gene cause severe cardiomyopathy with myocardial fibro-adipose replacement.
Perli E, Pisano A, Glasgow RIC, Carbo M, Hardy SA, Falkous G, He L, Cerbelli B, Pignataro MG, Zacara E, Re F, Della Monica PL, Morea V, Bonnen PE, Taylor RW, d'Amati G, Giordano C. Perli E, et al. Among authors: pignataro mg. Sci Rep. 2019 Mar 25;9(1):5108. doi: 10.1038/s41598-019-41483-9. Sci Rep. 2019. PMID: 30911037 Free PMC article.
Low-grade endotoxaemia enhances artery thrombus growth via Toll-like receptor 4: implication for myocardial infarction.
Carnevale R, Sciarretta S, Valenti V, di Nonno F, Calvieri C, Nocella C, Frati G, Forte M, d'Amati G, Pignataro MG, Severino A, Cangemi R, Arrivi A, Dominici M, Mangieri E, Gaudio C, Tanzilli G, Violi F. Carnevale R, et al. Among authors: pignataro mg. Eur Heart J. 2020 Sep 1;41(33):3156-3165. doi: 10.1093/eurheartj/ehz893. Eur Heart J. 2020. PMID: 31898723
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