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COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells.
McHugh D, Sun B, Gutierrez-Muñoz C, Hernández-González F, Mellone M, Guiho R, Duran I, Pombo J, Pietrocola F, Birch J, Kallemeijn WW, Khadayate S, Dharmalingam G, Vernia S, Tate EW, Martínez-Barbera JP, Withers DJ, Thomas GJ, Serrano M, Gil J. McHugh D, et al. Among authors: pietrocola f. Nat Cell Biol. 2023 Dec;25(12):1804-1820. doi: 10.1038/s41556-023-01287-6. Epub 2023 Nov 27. Nat Cell Biol. 2023. PMID: 38012402 Free PMC article.
Human senescent fibroblasts trigger progressive lung fibrosis in mice.
Hernandez-Gonzalez F, Prats N, Ramponi V, López-Domínguez JA, Meyer K, Aguilera M, Muñoz Martín MI, Martínez D, Agusti A, Faner R, Sellarés J, Pietrocola F, Serrano M. Hernandez-Gonzalez F, et al. Among authors: pietrocola f. Aging (Albany NY). 2023 Jul 1;15(14):6641-6657. doi: 10.18632/aging.204825. Epub 2023 Jul 1. Aging (Albany NY). 2023. PMID: 37393107 Free PMC article.
Mucosal TLR5 activation controls healthspan and longevity.
Lim JS, Jeon EJ, Go HS, Kim HJ, Kim KY, Nguyen TQT, Lee DY, Kim KS, Pietrocola F, Hong SH, Lee SE, Kim KS, Park TS, Choi DH, Jeong YJ, Park JH, Kim HS, Min JJ, Kim YS, Park JT, Cho JH, Lee GW, Lee JH, Choy HE, Park SC, Lee CH, Rhee JH, Serrano M, Cho KA. Lim JS, et al. Among authors: pietrocola f. Nat Commun. 2024 Jan 2;15(1):46. doi: 10.1038/s41467-023-44263-2. Nat Commun. 2024. PMID: 38167804 Free PMC article.
A versatile method for the identification of senolytic compounds.
Annunziata C, Castoldi F, Jan S, Ang HX, Ristovska M, Melini S, Welch R, Riedel CG, Pietrocola F. Annunziata C, et al. Among authors: pietrocola f. Cell Stress. 2023 Dec 11;7(12):105-111. doi: 10.15698/cst2023.12.292. eCollection 2023 Dec. Cell Stress. 2023. PMID: 38145234 Free PMC article.
Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair.
Kovatcheva M, Melendez E, Chondronasiou D, Pietrocola F, Bernad R, Caballe A, Junza A, Capellades J, Holguín-Horcajo A, Prats N, Durand S, Rovira M, Yanes O, Stephan-Otto Attolini C, Kroemer G, Serrano M. Kovatcheva M, et al. Among authors: pietrocola f. Nat Metab. 2023 Nov;5(11):1911-1930. doi: 10.1038/s42255-023-00916-6. Epub 2023 Nov 16. Nat Metab. 2023. PMID: 37973897 Free PMC article.
Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, Balachandran S, Bano D, Barlev NA, Bartek J, Bazan NG, Becker C, Bernassola F, Bertrand MJM, Bianchi ME, Blagosklonny MV, Blander JM, Blandino G, Blomgren K, Borner C, Bortner CD, Bove P, Boya P, Brenner C, Broz P, Brunner T, Damgaard RB, Calin GA, Campanella M, Candi E, Carbone M, Carmona-Gutierrez D, Cecconi F, Chan FK, Chen GQ, Chen Q, Chen YH, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Ciliberto G, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Daugaard M, Dawson TM, Dawson VL, De Maria R, De Strooper B, Debatin KM, Deberardinis RJ, Degterev A, Del Sal G, Deshmukh M, Di Virgilio F, Diederich M, Dixon SJ, Dynlacht BD, El-Deiry WS, Elrod JW, Engeland K, Fimia GM, Galassi C, Ganini C, Garcia-Saez AJ, Garg AD, Garrido C, Gavathiotis E, Gerlic M, Ghosh S, Green DR, Greene LA, Gronemeyer H, Häcker G, Hajnóczky G, Hardwick JM, Haupt Y, He S, Heery DM, Hengartner MO, Hetz C, Hildeman DA, Ichijo H, Inoue S, Jäättelä M, Janic A, Joseph B, Jost PJ, Kanneganti TD, Karin M, Kashkar H, Kaufmann T,… See abstract for full author list ➔ Vitale I, et al. Among authors: pietrocola f. Cell Death Differ. 2023 May;30(5):1097-1154. doi: 10.1038/s41418-023-01153-w. Epub 2023 Apr 26. Cell Death Differ. 2023. PMID: 37100955 Free PMC article. Review.
Meta-hallmarks of aging and cancer.
López-Otín C, Pietrocola F, Roiz-Valle D, Galluzzi L, Kroemer G. López-Otín C, et al. Among authors: pietrocola f. Cell Metab. 2023 Jan 3;35(1):12-35. doi: 10.1016/j.cmet.2022.11.001. Cell Metab. 2023. PMID: 36599298 Free article. Review.
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