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TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.
Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J. Davizon-Castillo P, et al. Among authors: pietras em. Blood. 2019 Aug 29;134(9):727-740. doi: 10.1182/blood.2019000200. Epub 2019 Jul 16. Blood. 2019. PMID: 31311815 Free PMC article.
The importance of tying up loose (DNA) ends.
Pietras EM. Pietras EM. Blood. 2017 May 4;129(18):2457-2458. doi: 10.1182/blood-2017-03-773184. Blood. 2017. PMID: 28473409 Free PMC article.
Ezh2 spares KitL from the cutter.
Pietras EM. Pietras EM. Blood. 2018 May 17;131(20):2180-2181. doi: 10.1182/blood-2018-04-841890. Blood. 2018. PMID: 29773542 Free article. No abstract available.
ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes.
Fisher MH, Kirkpatrick GD, Stevens B, Jones C, Callaghan M, Rajpurkar M, Fulbright J, Cooper MA, Rowley J, Porter CC, Gutierrez-Hartmann A, Jones K, Jordan C, Pietras EM, Di Paola J. Fisher MH, et al. Among authors: pietras em. JCI Insight. 2020 Sep 17;5(18):e140332. doi: 10.1172/jci.insight.140332. JCI Insight. 2020. PMID: 32841218 Free PMC article.
Extinguishing the Embers: Targeting AML Metabolism.
Culp-Hill R, D'Alessandro A, Pietras EM. Culp-Hill R, et al. Among authors: pietras em. Trends Mol Med. 2021 Apr;27(4):332-344. doi: 10.1016/j.molmed.2020.10.001. Epub 2020 Oct 26. Trends Mol Med. 2021. PMID: 33121874 Free PMC article. Review.
The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity.
Cavalli G, Tengesdal IW, Gresnigt M, Nemkov T, Arts RJW, Domínguez-Andrés J, Molteni R, Stefanoni D, Cantoni E, Cassina L, Giugliano S, Schraa K, Mills TS, Pietras EM, Eisenmensser EZ, Dagna L, Boletta A, D'Alessandro A, Joosten LAB, Netea MG, Dinarello CA. Cavalli G, et al. Among authors: pietras em. Cell Rep. 2021 Apr 6;35(1):108955. doi: 10.1016/j.celrep.2021.108955. Cell Rep. 2021. PMID: 33826894 Free article.
PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress.
Chavez JS, Rabe JL, Loeffler D, Higa KC, Hernandez G, Mills TS, Ahmed N, Gessner RL, Ke Z, Idler BM, Niño KE, Kim H, Myers JR, Stevens BM, Davizon-Castillo P, Jordan CT, Nakajima H, Ashton J, Welner RS, Schroeder T, DeGregori J, Pietras EM. Chavez JS, et al. Among authors: pietras em. J Exp Med. 2021 Jun 7;218(6):e20201169. doi: 10.1084/jem.20201169. J Exp Med. 2021. PMID: 33857288 Free PMC article.
66 results