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The Glucocorticoid Receptor in Osterix-Expressing Cells Regulates Bone Mass, Bone Marrow Adipose Tissue, and Systemic Metabolism in Female Mice During Aging.
Pierce JL, Sharma AK, Roberts RL, Yu K, Irsik DL, Choudhary V, Dorn JS, Bensreti H, Benson RD Jr, Kaiser H, Khayrullin A, Davis C, Wehrle CJ, Johnson MH, Bollag WB, Hamrick MW, Shi X, Isales CM, McGee-Lawrence ME. Pierce JL, et al. J Bone Miner Res. 2022 Feb;37(2):285-302. doi: 10.1002/jbmr.4468. Epub 2021 Nov 24. J Bone Miner Res. 2022. PMID: 34747055 Free PMC article.
Kynurenine, a Tryptophan Metabolite That Accumulates With Age, Induces Bone Loss.
Refaey ME, McGee-Lawrence ME, Fulzele S, Kennedy EJ, Bollag WB, Elsalanty M, Zhong Q, Ding KH, Bendzunas NG, Shi XM, Xu J, Hill WD, Johnson MH, Hunter M, Pierce JL, Yu K, Hamrick MW, Isales CM. Refaey ME, et al. Among authors: pierce jl. J Bone Miner Res. 2017 Nov;32(11):2182-2193. doi: 10.1002/jbmr.3224. Epub 2017 Aug 14. J Bone Miner Res. 2017. PMID: 28727234 Free PMC article.
The glucocorticoid receptor in osteoprogenitors regulates bone mass and marrow fat.
Pierce JL, Ding KH, Xu J, Sharma AK, Yu K, Del Mazo Arbona N, Rodriguez-Santos Z, Bernard P, Bollag WB, Johnson MH, Hamrick MW, Begun DL, Shi XM, Isales CM, McGee-Lawrence ME. Pierce JL, et al. J Endocrinol. 2019 Jul 1:JOE-19-0230.R1. doi: 10.1530/JOE-19-0230. Online ahead of print. J Endocrinol. 2019. PMID: 31370004 Free PMC article.
Picolinic acid, a tryptophan oxidation product, does not impact bone mineral density but increases marrow adiposity.
Ding K, McGee-Lawrence ME, Kaiser H, Sharma AK, Pierce JL, Irsik DL, Bollag WB, Xu J, Zhong Q, Hill W, Shi XM, Fulzele S, Kennedy EJ, Elsalanty M, Hamrick MW, Isales CM. Ding K, et al. Among authors: pierce jl. Exp Gerontol. 2020 May;133:110885. doi: 10.1016/j.exger.2020.110885. Epub 2020 Feb 20. Exp Gerontol. 2020. PMID: 32088397 Free PMC article.
Age-related increase of kynurenine enhances miR29b-1-5p to decrease both CXCL12 signaling and the epigenetic enzyme Hdac3 in bone marrow stromal cells.
Elmansi AM, Hussein KA, Herrero SM, Periyasamy-Thandavan S, Aguilar-Pérez A, Kondrikova G, Kondrikov D, Eisa NH, Pierce JL, Kaiser H, Ding KH, Walker AL, Jiang X, Bollag WB, Elsalanty M, Zhong Q, Shi XM, Su Y, Johnson M, Hunter M, Reitman C, Volkman BF, Hamrick MW, Isales CM, Fulzele S, McGee-Lawrence ME, Hill WD. Elmansi AM, et al. Among authors: pierce jl. Bone Rep. 2020 Apr 23;12:100270. doi: 10.1016/j.bonr.2020.100270. eCollection 2020 Jun. Bone Rep. 2020. PMID: 32395570 Free PMC article.
90 results