Pickkers P - Search Results

1

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.

Domínguez-Andrés J, Novakovic B, Li Y, Scicluna BP, Gresnigt MS, Arts RJW, Oosting M, Moorlag SJCFM, Groh LA, Zwaag J, Koch RM, Ter Horst R, Joosten LAB, Wijmenga C, Michelucci A, van der Poll T, Kox M, Pickkers P, Kumar V, Stunnenberg H, Netea MG. Domínguez-Andrés J, et al. Among authors: pickkers p. Cell Metab. 2019 Jan 8;29(1):211-220.e5. doi: 10.1016/j.cmet.2018.09.003. Epub 2018 Oct 4. Cell Metab. 2019. PMID: 30293776 Free article.

2

TNFalpha and IL-1beta exert no direct vasoactivity in human isolated resistance arteries.

Pickkers P, Netea MG, van der Meer JW, Smits P. Pickkers P, et al. Cytokine. 2002 Dec 7;20(5):244-6. doi: 10.1006/cyto.2002.2004. Cytokine. 2002. PMID: 12550110

3

Hypothesis: Normalisation of cytokine dysbalance explains the favourable effects of strict glucose regulation in the critically ill.

Pickkers P, Hoedemaekers A, Netea MG, de Galan BE, Smits P, van der Hoeven JG, van Deuren M. Pickkers P, et al. Neth J Med. 2004 May;62(5):143-50. Neth J Med. 2004. PMID: 15366696 Free article. Review.

4

Iso-osmolar prehydration shifts the cytokine response towards a more anti-inflammatory balance in human endotoxemia.

Dorresteijn MJ, van Eijk LT, Netea MG, Smits P, van der Hoeven JG, Pickkers P. Dorresteijn MJ, et al. Among authors: pickkers p. J Endotoxin Res. 2005;11(5):287-93. doi: 10.1179/096805105X58715. J Endotoxin Res. 2005. PMID: 16263001 Clinical Trial.

5

IFN-gamma is not induced through increased plasma concentrations of interleukin-12/interleukin-18 during human endotoxemia.

Dorresteijn MJ, Pickkers P, Netea MG, Van der Hoeven JG. Dorresteijn MJ, et al. Among authors: pickkers p. Eur Cytokine Netw. 2005 Sep;16(3):191-3. Eur Cytokine Netw. 2005. PMID: 16266858 Free article.

6

Intensive insulin therapy does not alter the inflammatory response in patients undergoing coronary artery bypass grafting: a randomized controlled trial [ISRCTN95608630].

Hoedemaekers CW, Pickkers P, Netea MG, van Deuren M, Van der Hoeven JG. Hoedemaekers CW, et al. Among authors: pickkers p. Crit Care. 2005;9(6):R790-7. doi: 10.1186/cc3911. Epub 2005 Nov 16. Crit Care. 2005. PMID: 16356228 Free PMC article. Clinical Trial.

7

Plasma obtained during human endotoxemia increases endothelial albumin permeability in vitro.

van Eijk LT, Nooteboom A, Hendriks T, Sprong T, Netea MG, Smits P, van der Hoeven JG, Pickkers P. van Eijk LT, et al. Among authors: pickkers p. Shock. 2006 Apr;25(4):358-62. doi: 10.1097/01.shk.0000209527.35743.b0. Shock. 2006. PMID: 16670637

8

Gender differences in the innate immune response and vascular reactivity following the administration of endotoxin to human volunteers.

van Eijk LT, Dorresteijn MJ, Smits P, van der Hoeven JG, Netea MG, Pickkers P. van Eijk LT, et al. Among authors: pickkers p. Crit Care Med. 2007 Jun;35(6):1464-9. doi: 10.1097/01.CCM.0000266534.14262.E8. Crit Care Med. 2007. PMID: 17452928 Clinical Trial.

9

Does subarachnoid haemorrhage affect the innate immune response?

Kox M, Pompe J, Hoedemaekers A, Pickkers P. Kox M, et al. Among authors: pickkers p. Intensive Care Med. 2007 Jul;33(7):1303. doi: 10.1007/s00134-007-0664-5. Epub 2007 May 25. Intensive Care Med. 2007. PMID: 17530221 Free PMC article. No abstract available.

10

Increased vagal tone accounts for the observed immune paralysis in patients with traumatic brain injury.

Kox M, Pompe JC, Pickkers P, Hoedemaekers CW, van Vugt AB, van der Hoeven JG. Kox M, et al. Among authors: pickkers p. Neurology. 2008 Feb 5;70(6):480-5. doi: 10.1212/01.wnl.0000279479.69502.3e. Neurology. 2008. PMID: 18250293 Free article. Review.

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