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Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer.
Guerra E, Trerotola M, Relli V, Lattanzio R, Tripaldi R, Vacca G, Ceci M, Boujnah K, Garbo V, Moschella A, Zappacosta R, Simeone P, de Lange R, Weidle UH, Rotelli MT, Picciariello A, Depalo R, Querzoli P, Pedriali M, Bianchini E, Angelucci D, Pizzicannella G, Di Loreto C, Piantelli M, Antolini L, Sun XF, Altomare DF, Alberti S. Guerra E, et al. Among authors: piantelli m. Neoplasia. 2021 Sep;23(9):898-911. doi: 10.1016/j.neo.2021.07.002. Epub 2021 Jul 25. Neoplasia. 2021. PMID: 34320447 Free PMC article.
Trop-2 is a determinant of breast cancer survival.
Ambrogi F, Fornili M, Boracchi P, Trerotola M, Relli V, Simeone P, La Sorda R, Lattanzio R, Querzoli P, Pedriali M, Piantelli M, Biganzoli E, Alberti S. Ambrogi F, et al. Among authors: piantelli m. PLoS One. 2014 May 13;9(5):e96993. doi: 10.1371/journal.pone.0096993. eCollection 2014. PLoS One. 2014. PMID: 24824621 Free PMC article.
Trop-2 Induces Tumor Growth Through AKT and Determines Sensitivity to AKT Inhibitors.
Guerra E, Trerotola M, Tripaldi R, Aloisi AL, Simeone P, Sacchetti A, Relli V, D'Amore A, La Sorda R, Lattanzio R, Piantelli M, Alberti S. Guerra E, et al. Among authors: piantelli m. Clin Cancer Res. 2016 Aug 15;22(16):4197-205. doi: 10.1158/1078-0432.CCR-15-1701. Epub 2016 Mar 28. Clin Cancer Res. 2016. PMID: 27022065
Upregulation of Trop-2 quantitatively stimulates human cancer growth.
Trerotola M, Cantanelli P, Guerra E, Tripaldi R, Aloisi AL, Bonasera V, Lattanzio R, de Lange R, Weidle UH, Piantelli M, Alberti S. Trerotola M, et al. Among authors: piantelli m. Oncogene. 2013 Jan 10;32(2):222-33. doi: 10.1038/onc.2012.36. Epub 2012 Feb 20. Oncogene. 2013. PMID: 22349828
The Trop-2 signalling network in cancer growth.
Guerra E, Trerotola M, Aloisi AL, Tripaldi R, Vacca G, La Sorda R, Lattanzio R, Piantelli M, Alberti S. Guerra E, et al. Among authors: piantelli m. Oncogene. 2013 Mar 21;32(12):1594-600. doi: 10.1038/onc.2012.151. Epub 2012 May 7. Oncogene. 2013. PMID: 22562244
Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion.
Guerra E, Relli V, Ceci M, Tripaldi R, Simeone P, Aloisi AL, Pantalone L, La Sorda R, Lattanzio R, Sacchetti A, Havas K, Guarnieri S, Vergara D, Fournier I, Salzet M, Tinari N, Piantelli M, Trerotola M, Alberti S. Guerra E, et al. Among authors: piantelli m. Oncogene. 2022 Mar;41(12):1795-1808. doi: 10.1038/s41388-022-02220-1. Epub 2022 Feb 7. Oncogene. 2022. PMID: 35132180
189 results