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Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y14R Antagonist.
Wen Z, Salmaso V, Jung YH, Phung NB, Gopinatth V, Shah Q, Patterson AT, Randle JCR, Chen Z, Salvemini D, Lieberman DI, Whitehead GS, Karcz TP, Cook DN, Jacobson KA. Wen Z, et al. Among authors: phung nb. J Med Chem. 2022 Feb 24;65(4):3434-3459. doi: 10.1021/acs.jmedchem.1c01964. Epub 2022 Feb 3. J Med Chem. 2022. PMID: 35113556 Free PMC article.
Structure-Activity Relationship of Heterocyclic P2Y14 Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres.
Jung YH, Salmaso V, Wen Z, Bennett JM, Phung NB, Lieberman DI, Gopinatth V, Randle JCR, Chen Z, Salvemini D, Karcz TP, Cook DN, Jacobson KA. Jung YH, et al. Among authors: phung nb. J Med Chem. 2021 Apr 22;64(8):5099-5122. doi: 10.1021/acs.jmedchem.1c00164. Epub 2021 Mar 31. J Med Chem. 2021. PMID: 33787273 Free PMC article.
P2Y14 Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model.
Mufti F, Jung YH, Giancotti LA, Yu J, Chen Z, Phung NB, Jacobson KA, Salvemini D. Mufti F, et al. Among authors: phung nb. ACS Med Chem Lett. 2020 Apr 30;11(6):1281-1286. doi: 10.1021/acsmedchemlett.0c00115. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32551012 Free PMC article.