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Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response.
Béguelin W, Teater M, Meydan C, Hoehn KB, Phillip JM, Soshnev AA, Venturutti L, Rivas MA, Calvo-Fernández MT, Gutierrez J, Camarillo JM, Takata K, Tarte K, Kelleher NL, Steidl C, Mason CE, Elemento O, Allis CD, Kleinstein SH, Melnick AM. Béguelin W, et al. Among authors: phillip jm. Cancer Cell. 2020 May 11;37(5):655-673.e11. doi: 10.1016/j.ccell.2020.04.004. Cancer Cell. 2020. PMID: 32396861 Free PMC article.
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Yusufova N, Kloetgen A, Teater M, Osunsade A, Camarillo JM, Chin CR, Doane AS, Venters BJ, Portillo-Ledesma S, Conway J, Phillip JM, Elemento O, Scott DW, Béguelin W, Licht JD, Kelleher NL, Staudt LM, Skoultchi AI, Keogh MC, Apostolou E, Mason CE, Imielinski M, Schlick T, David Y, Tsirigos A, Allis CD, Soshnev AA, Cesarman E, Melnick AM. Yusufova N, et al. Among authors: phillip jm. Nature. 2021 Jan;589(7841):299-305. doi: 10.1038/s41586-020-3017-y. Epub 2020 Dec 9. Nature. 2021. PMID: 33299181 Free PMC article.
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.
Venturutti L, Teater M, Zhai A, Chadburn A, Babiker L, Kim D, Béguelin W, Lee TC, Kim Y, Chin CR, Yewdell WT, Raught B, Phillip JM, Jiang Y, Staudt LM, Green MR, Chaudhuri J, Elemento O, Farinha P, Weng AP, Nissen MD, Steidl C, Morin RD, Scott DW, Privé GG, Melnick AM. Venturutti L, et al. Among authors: phillip jm. Cell. 2020 Jul 23;182(2):297-316.e27. doi: 10.1016/j.cell.2020.05.049. Epub 2020 Jul 2. Cell. 2020. PMID: 32619424 Free PMC article.
BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress.
Fernando TM, Marullo R, Pera Gresely B, Phillip JM, Yang SN, Lundell-Smith G, Torregroza I, Ahn H, Evans T, Győrffy B, Privé GG, Hirano M, Melnick AM, Cerchietti L. Fernando TM, et al. Among authors: phillip jm. Cancer Discov. 2019 May;9(5):662-679. doi: 10.1158/2159-8290.CD-17-1444. Epub 2019 Feb 18. Cancer Discov. 2019. PMID: 30777872 Free PMC article.
Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures.
Kotlov N, Bagaev A, Revuelta MV, Phillip JM, Cacciapuoti MT, Antysheva Z, Svekolkin V, Tikhonova E, Miheecheva N, Kuzkina N, Nos G, Tabbo F, Frenkel F, Ghione P, Tsiper M, Almog N, Fowler N, Melnick AM, Leonard JP, Inghirami G, Cerchietti L. Kotlov N, et al. Among authors: phillip jm. Cancer Discov. 2021 Jun;11(6):1468-1489. doi: 10.1158/2159-8290.CD-20-0839. Epub 2021 Feb 4. Cancer Discov. 2021. PMID: 33541860 Free PMC article.
Endothelial cell-leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities.
Cappelli LV, Fiore D, Phillip JM, Yoffe L, Di Giacomo F, Chiu W, Hu Y, Kayembe C, Ginsberg M, Consolino L, Barcia Duran JG, Zamponi N, Melnick AM, Boccalatte F, Tam W, Elemento O, Chiaretti S, Guarini A, Foà R, Cerchietti L, Rafii S, Inghirami G. Cappelli LV, et al. Among authors: phillip jm. Blood. 2023 Feb 2;141(5):503-518. doi: 10.1182/blood.2022015414. Blood. 2023. PMID: 35981563 Free PMC article.
Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy.
Dalton T, Doubrovina E, Pankov D, Reynolds R, Scholze H, Selvakumar A, Vizconde T, Savalia B, Dyomin V, Weigel C, Oakes CC, Alonso A, Elemento O, Pan H, Phillip JM, O'Reilly RJ, Gewurz BE, Cesarman E, Giulino-Roth L. Dalton T, et al. Among authors: phillip jm. Blood. 2020 May 21;135(21):1870-1881. doi: 10.1182/blood.2019004126. Blood. 2020. PMID: 32157281 Free PMC article.
Oncogenic HSP90 Facilitates Metabolic Alterations in Aggressive B-cell Lymphomas.
Calvo-Vidal MN, Zamponi N, Krumsiek J, Stockslager MA, Revuelta MV, Phillip JM, Marullo R, Tikhonova E, Kotlov N, Patel J, Yang SN, Yang L, Taldone T, Thieblemont C, Leonard JP, Martin P, Inghirami G, Chiosis G, Manalis SR, Cerchietti L. Calvo-Vidal MN, et al. Among authors: phillip jm. Cancer Res. 2021 Oct 15;81(20):5202-5216. doi: 10.1158/0008-5472.CAN-21-2734. Epub 2021 Sep 3. Cancer Res. 2021. PMID: 34479963 Free PMC article.
38 results