Phan TN - Search Results

1

Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites.

Stampolaki M, Malwal SR, Alvarez-Cabrera N, Gao Z, Moniruzzaman M, Babii SO, Naziris N, Rey-Cibati A, Valladares-Delgado M, Turcu AL, Baek KH, Phan TN, Lee H, Alcaraz M, Watson S, van der Watt M, Coertzen D, Efstathiou N, Chountoulesi M, Shoen CM, Papanastasiou IP, Brea J, Cynamon MH, Birkholtz LM, Kremer L, No JH, Vázquez S, Benaim G, Demetzos C, Zgurskaya HI, Dick T, Oldfield E, Kolocouris AD. Stampolaki M, et al. Among authors: phan tn. ACS Infect Dis. 2023 Feb 10;9(2):342-364. doi: 10.1021/acsinfecdis.2c00537. Epub 2023 Jan 27. ACS Infect Dis. 2023. PMID: 36706233 Free PMC article.

2

In Vitro and in Vivo Activity of mTOR Kinase and PI3K Inhibitors Against Leishmania donovani and Trypanosoma brucei.

Phan TN, Baek KH, Lee N, Byun SY, Shum D, No JH. Phan TN, et al. Molecules. 2020 Apr 23;25(8):1980. doi: 10.3390/molecules25081980. Molecules. 2020. PMID: 32340370 Free PMC article.

3

Discovery of Leishmania donovani topoisomerase IB selective inhibitors by targeting protein-protein interactions between the large and small subunits.

Lee H, Baek KH, Phan TN, Park IS, Lee S, Kim J, No JH. Lee H, et al. Among authors: phan tn. Biochem Biophys Res Commun. 2021 Sep 10;569:193-198. doi: 10.1016/j.bbrc.2021.07.019. Epub 2021 Jul 10. Biochem Biophys Res Commun. 2021. PMID: 34256188

4

Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani.

Hassan AHE, Phan TN, Yoon S, Lee CJ, Jeon HR, Kim SH, No JH, Lee YS. Hassan AHE, et al. Among authors: phan tn. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1922-1930. doi: 10.1080/14756366.2021.1969385. J Enzyme Inhib Med Chem. 2021. PMID: 34425714 Free PMC article.

5

In Vivo Efficacy of SQ109 against Leishmania donovani, Trypanosoma spp. and Toxoplasma gondii and In Vitro Activity of SQ109 Metabolites.

Baek KH, Phan TN, Malwal SR, Lee H, Li ZH, Moreno SNJ, Oldfield E, No JH. Baek KH, et al. Among authors: phan tn. Biomedicines. 2022 Mar 14;10(3):670. doi: 10.3390/biomedicines10030670. Biomedicines. 2022. PMID: 35327472 Free PMC article.

6

Design, Rational Repurposing, Synthesis, In Vitro Evaluation, Homology Modeling and In Silico Study of Sulfuretin Analogs as Potential Antileishmanial Hit Compounds.

Hassan AHE, Phan TN, Choi Y, Moon S, No JH, Lee YS. Hassan AHE, et al. Among authors: phan tn. Pharmaceuticals (Basel). 2022 Aug 26;15(9):1058. doi: 10.3390/ph15091058. Pharmaceuticals (Basel). 2022. PMID: 36145279 Free PMC article.

7

Discovery of novel Leishmania major trypanothione synthetase inhibitors by high-throughput screening.

Phan TN, Park KP, Benítez D, Comini MA, Shum D, No JH. Phan TN, et al. Biochem Biophys Res Commun. 2022 Dec 31;637:308-313. doi: 10.1016/j.bbrc.2022.11.044. Epub 2022 Nov 17. Biochem Biophys Res Commun. 2022. PMID: 36413853

8

Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies.

Hassan AHE, Mahmoud K, Phan TN, Shaldam MA, Lee CH, Kim YJ, Cho SB, Bayoumi WA, El-Sayed SM, Choi Y, Moon S, No JH, Lee YS. Hassan AHE, et al. Among authors: phan tn. Eur J Med Chem. 2023 Mar 15;250:115211. doi: 10.1016/j.ejmech.2023.115211. Epub 2023 Feb 14. Eur J Med Chem. 2023. PMID: 36827952

9

Design, synthesis, and repurposing of O⁶-aminoalkyl-sulfuretin analogs towards discovery of potential lead compounds as antileishmanial agents.

Hassan AHE, Phan TN, Moon S, Lee CH, Kim YJ, Cho SB, El-Sayed SM, Choi Y, No JH, Lee YS. Hassan AHE, et al. Among authors: phan tn. Eur J Med Chem. 2023 May 5;251:115256. doi: 10.1016/j.ejmech.2023.115256. Epub 2023 Mar 9. Eur J Med Chem. 2023. PMID: 36944273

10

Rational repurposing, synthesis, in vitro and in silico studies of chromone-peptidyl hybrids as potential agents against Leishmania donovani.

Hassan AHE, Bayoumi WA, El-Sayed SM, Phan TN, Kim YJ, Lee CH, Cho SB, Oh T, Ham G, Mahmoud K, No JH, Lee YS. Hassan AHE, et al. Among authors: phan tn. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2229071. doi: 10.1080/14756366.2023.2229071. J Enzyme Inhib Med Chem. 2023. PMID: 37381756 Free PMC article.

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